Amino acids are vital substances that are mostly ingested through food. There are hundreds of different amino acids, but in terms of diet and nutrition, there are only 22 you need to be concerned with. Collectively amino acids are used to support nearly every physiological function, including muscle growth and athletic endurance.
Dietary amino acids
The 22 amino acids that relate to diet and nutrition are called "standard amino acids." They're subdivided further into two groups: essential and nonessential.
Essential amino acids
There are nine essential amino acids. These must be taken in through food or supplementation since the body has no means of synthesizing them. They are:
| Essential amino acid | How it works |
|---|---|
| Histidine | Supports the central nervous and digestive systems.[1] |
| Isoleucine* | Promotes the use of glucose and protein by the muscles during exercise, and regulates blood sugar levels.[2] |
| Leucine* | Mostly used for protein synthesis in muscle tissues, but also improves glucose uptake and is necessary to form blood cells.[3] This is our favorite amino acid due to its muscle-building and endurance-boosting effects. |
| Valine* | Converts fatty acids to energy and helps the digestive system absorb calcium.[4] |
| Lysine | Converts fatty acids to energy and helps the digestive system absorb calcium.[4] |
| Methionine | Very important to kidney cells, methionine is also a precursor of creatine, taurine, and lecithin.[5] |
| Phenylalanine | Helps to regulate mood and cognitive function.[6] |
| Threonine | Needed to form collagen and tooth enamel, it also supports the immune system.[7] |
| Tryptophan | While it's probably most familiar as a sleep aid, tryptophan is also a precursor for the synthesis of auxin, niacin, and serotonin. It is also needed to regulate nitrogen levels.[8] |
*Also known as branched-chain amino acids (BCAAs).
Nonessential amino acids
The remaining 13 amino acids are considered "nonessential" as the body can synthesize them from other sources. Serine
| Essential amino acid | How it works | |
|---|---|---|
| Alanine | Used to form glucose in the liver, it's also needed for sugar and acid digestion and for immune system support.[10] | |
| Arginine | A necessary precursor for the nitric oxide synthesis, helps in both tissue and bone repair, supports the immune system, and removes ammonia from the body.[11] | |
| Asparagine | Aids in metabolic control of cell functions in nerve and brain tissue.[12] | |
| Aspartic acid | Is thought to be a neurotransmitter, but research is not yet conclusive.[13] | |
| Cysteine | A precursor to glutamic acid, glycine, and sulfide.[14] | |
| Glutamic acid | Necessary for metabolic function, removal of excess nitrogen and is the most common neurotransmitter in the body.[15] | |
| Glutamine | Needed for protein synthesis, pH balance in the kidneys, cellular energy, and as a transporter of nitrogen, carbon, and ammonia.[16] | |
| Glycine | Needed to digest proteins and is a common neurotransmitter.[17] | |
| Ornithine | Necessary to support the urea cycle and may also play a role in reducing the feeling of fatigue.[18] | |
| Proline | Needed for regular joint and tendon function and also for the formation of collagen.[19] | |
| Selenocysteine | Serves the same functions as cysteine but also plays a role in protein synthesis.[20] | |
| Serine | Needed for metabolic function and also functions as a neurotransmitter.[21] | |
| Tyrosine | Needed to synthesize melanin, epinephrine, and thyroid hormones.[22]td> |
Supplementation
There are hundreds of different amino acids, but in terms of diet and nutrition, only 22 you need to be concerned with.
As far as diet goes, supplementation with essential amino acids is generally only necessary for certain medical conditions or to support a vegetarian/vegan diet.
The BCAAs can help to promote muscle growth and speed recovery, however, so you'll frequently see them included in pre-workout formulas and protein mixes. Supplements that emphasize BCAAs are usually formulated in a ratio that expresses how much relative leucine, isoleucine, and valine they have. For example, one common formulation you'll see in supplements is leucine in a 2:1:1 ratio. This simply means there's twice as much leucine as there are the other two BCAAs.
Glutamine is frequently featured in supplements under the claim that it is a vital muscle fuel source that is depleted by exercise. It's still unclear whether glutamine supplementation before or during a workout has any effect on muscle performance, however. Two placebo studies found no effect of glutamine supplementation whatsoever in weightlifting tests.[23,24] However, a study of long-distance runners found that glutamine seemed to bolster their strained immune systems after a marathon run.[25]
Beta-alanine is a useful supplement for upping the intensity of your workout. It increases the availability of carnosine to muscle tissue. Carnosine regulates the pH balance of muscles by scooping up the hydrogen ions generated when they're in use, and this amounts to a boost in both muscle output and endurance. While there's no studies that have shown carnosine to directly influence the growth of muscles, supplementation does allow for longer sets at higher intensity. Concurrent carnosine supplementation is necessary to see this benefit, though - beta-alanine alone doesn't have any particular effect.
The L-carnitine family provides energy at a cellular level. It's made up of several sub-compounds that have different beneficial effects. Acetyl L-carnitine (ALCAR) is a neurotransmitter that improves cognitive function and reduces feelings of fatigue. Propionyl-L-carnitine (PLCAR) has been shown in rat studies to promote the burning of fat as energy to support working muscle tissue. L-carnitine L-tartrate is an antioxidant that eases soreness after exercise. And glycine propionyl-L-carnitine (GPLC) improves blood flow and oxygen delivery to muscle tissue.
Food sources
Both the essential and the non-essential amino acids are found in foods that are rich in protein.
If you're meeting your overall daily nutritional requirements for protein and carbohydrates, your body will be able to synthesize all of the non-essential amino acids that it needs.
Meat, eggs, poultry, and fish are the best complete sources of the nine essential amino acids. Beans are also good sources, particularly pinto, kidney, and soy. A number of vegetables do contain complete proteins, but in much smaller amounts than other food sources.
Where to buy
You can find amino acid supplements here at PricePlow at 30% to 50% off of retail prices. We typically enjoy powdered-based formulas more, especially for workouts, since they are more convenient, tastier, and typically cost less per gram.
References
- PubChem; "Histidine;" 2014
- PubChem; "Isoleucine;" 2014
- PubChem; "Leucine;" 2014
- PubChem; "Lysine;" 2014
- PubChem; "Methionine;" 2014
- PubChem; "Phenylalanine;" 2014
- PubChem; "Threonine;" 2014
- PubChem; "Tryptophan;" 2014
- PubChem; "Valine;" 2014
- PubChem; "Alanine;" 2014
- PubChem; "Arginine;" 2014
- PubChem; "Asparagine;" 2014
- PubChem; "Aspartic Acid;" 2014
- PubChem; "Cysteine;" 2014
- PubChem; "Glutamic Acid;" 2014
- PubChem; "Glutamine;" 2014
- PubChem; "Glycine;" 2014
- PubChem; "Ornithine;" 2014
- PubChem; "Proline;" 2014
- PubChem; "Selenocysteine;" 2014
- PubChem; "Serine;" 2014
- PubChem; "Tyrosine" 2014
- Candow, D, et. al; European Journal of Applied Physiology; "Effect of glutamine supplementation combined with resistance training in young adults;" December 2001
- Antonio, J, et. al; Journal of Strength and Conditioning Research; "The effects of high-dose glutamine ingestion on weightlifting performance;" February 2002
- Castell, L, et. al; Nutrition; "The effects of oral glutamine supplementation on athletes after prolonged, exhaustive exercise;" July 1997
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Nootropics Depot L-Carnosine was created.
Category: Carnosine -
Dec 14, 2024 
Product News
Nootropics Depot Taurine was created.
Category: Taurine -
Dec 14, 2024 
Product News
Nootropics Depot N-Acetyl L-Cysteine was created.
Category: N-Acetyl-Cysteine -
Dec 14, 2024 
Product News
Nootropics Depot L-Tyrosine was created.
Category: L-Tyrosine -
Dec 14, 2024 
Product News
Nootropics Depot S-Acetyl L-Glutathione was created.
Category: Glutathione -
Dec 14, 2024 
Product News
Nootropics Depot Acetyl L-Carnitine was created.
Category: Acetyl L-Carnitine -
Dec 14, 2024 
Product News
MTN OPS Beta-Alanine was created.
Category: Beta Alanine -
Dec 12, 2024 
Product News
Mutant Hardcore BCAA was created.
Category: BCAA Powder -
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Nugenix L-Arginine was created.
Category: L-Arginine -
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Dec 05, 2024 
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Dec 05, 2024 
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Leviathan Nutrition Liposomal Glutathione was created.
Category: Glutathione -
Dec 03, 2024 
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Nov 28, 2024 
YouTube Video
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Nov 27, 2024 
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DAS Labs essentials Amino Acids was created.
Category: Essential Amino Acids -
Nov 23, 2024 
YouTube Video
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Nov 22, 2024 
TikTok Video
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Nov 21, 2024 
Product News
Arms Race Nutrition Daily Amino was created.
Category: Essential Amino Acids -
Nov 20, 2024 
YouTube Video
Introducing Mindvalley States: Supplements to Support Your State of Mind -
Nov 19, 2024 
YouTube Video
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Nov 15, 2024 
Product News
Musclesport BCAA Revolution has new variations: Category: BCAA Powder -
Nov 09, 2024 
Product News
Nugenix L-Glutamine was created.
Category: Glutamine Pills -
Nov 08, 2024 
Product News
Nootropics Depot N-Acetyl L-Tyrosine was created.
Category: N-Acetyl L-Tyrosine -
Nov 07, 2024 
YouTube Video
Anti-Aging Creatine + HMB + GG Supplement! Designs for Health MyoStim -
Nov 06, 2024 
YouTube Video
ProSupps Infinite Pre-Workout: High Focus, Moderate Caffeine, Maximum Performance -
Nov 06, 2024 
YouTube Video
Legendary Flavor Drop: GHOST Legend V4 in Swedish Fish! -
Nov 01, 2024 
YouTube Video
Synnovo® by INNOBIO: Raising the Bar for Amino Acids -
Oct 25, 2024 
Blog Post
Redefining The Quality of Amino Acids with Synnovo® by INNOBIO
INNOBIO’s Synnovo® aminos set a new standard for quality. Perfect for RTD formulations or gym-goers mixing BCAAs and EAAs. -
Oct 24, 2024 
Product News
Nugenix L-Citrulline was created.
Category: Citrulline -
Oct 23, 2024 
Product News
DAS Labs Babe x Cara Loren BCAA was created.
Category: BCAA Powder -
Oct 19, 2024 
Product News
FinaFlex Beta Alanine was created.
Category: Beta Alanine -
Oct 19, 2024 
Product News
Mutant Gold Series EAA+BCAA Complete was created.
Categories: BCAA Powder, Essential Amino Acids -
Oct 18, 2024 
Product News
Labrada Pro Series EAA was created.
Category: Essential Amino Acids -
Oct 18, 2024 
Product News
Labrada Pro Series Glutamine was created.
Category: Glutamine Powder
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Amino Acid Price Alerts
The following price alerts are still active:
- Apr 24, 2025Swanson Glycine 8 Oz. dropped by 10% to $12.22 at iHerb.com
- Apr 23, 2025EVLution Nutrition BCAA 5000 30 Servings (only Cherry Limeade) dropped by 10% to $17.09 at iHerb.com
- Apr 22, 2025Gaspari Nutrition HMB 90 Capsules dropped by 17.5% to $21.99 at Muscle and Strength
- Apr 21, 2025Nutrex EAA+ Hydration 30 Servings (only Maui Twist) dropped by 10.5% to $34.00 at Muscle and Strength
- Apr 21, 2025Xtend Original 90 Servings (only Blue Raspberry Ice, Glacial Grape, Lemon Lime Squeeze, Watermelon Explosion) dropped by 8.1% to $90.00 at Muscle and Strength
- Apr 21, 2025Xtend Original 90 Servings (only Italian Blood Orange, Knockout Fruit Punch) dropped by 10% to $90.00 at Muscle and Strength
- Apr 21, 2025The Vitamin Shoppe GABA 180 Tablets dropped by 18.6% to $28.49 at iHerb.com
- Apr 20, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 30 Servings (only Fruit Punch) dropped by 21% to $29.99 at Walmart
- Apr 18, 2025Xtend Original 30 Servings (only Air Heads - Cherry, Fruit Punch, Green Apple, Lemon Lime Squeeze, Mango Madness, Orange Cream, Strawberry Kiwi Splash, Watermelon Explosion) dropped by 7.9% to $34.99 at Muscle and Strength
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 25 Servings (only Fruit Punch (Caffeinated)) dropped by 13.1% to $32.98 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 30 Servings (only Blue Raspberry) dropped by 13.1% to $32.98 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 30 Servings (only Mango Pineapple, Southern Sweet Tea) dropped by 21% to $29.99 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 10 Packets dropped by 28.6% to $14.99 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 25 Servings (only Southern Sweet Tea (Caffeinated)) dropped by 28.9% to $26.98 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 30 Servings (only Blueberry Lemonade) dropped by 18.7% to $29.99 at Walmart
- Apr 16, 2025Rich Piana 5% Nutrition ALL DAY YOU MAY 30 Servings (only Watermelon) dropped by 10.4% to $29.99 at Walmart
- Apr 12, 2025EVLution Nutrition BCAA Energy 30 Servings (only Green Apple) dropped by 35.2% to $14.24 at iHerb.com
- Apr 09, 2025Force Factor HMB 90 Tablets dropped by 9.1% to $19.99 at Muscle and Strength
- Apr 08, 2025GHOST BCAA 30 Servings (only Sour Patch Kids Blue Raspberry, Sour Patch Kids RedBerry) dropped by 20% to $22.40 at Ghost Lifestyle
- Apr 02, 2025Jarrow Formulas GABA Soothe 30 Vcaps dropped by 71% to $5.79 at AllStarHealth
- Mar 20, 2025EVLution Nutrition BCAA 5000 30 Servings (only Furious Grape) dropped by 37.2% to $13.19 at iHerb.com
- Mar 17, 2025NOW GABA 100 Vcaps (only 750mg) dropped by 11.8% to $8.99 at Muscle and Strength
- Mar 14, 2025Nutrex EAA+ Hydration 30 Servings (only Lemon Lime) dropped by 28.9% to $22.49 at DPS Nutrition
- Mar 14, 2025NutraBio HMB 120 Vcaps dropped by 9.9% to $19.80 at NutraBio
- Mar 10, 2025KAL GABA 120 Tablets dropped by 12.2% to $10.49 at iHerb.com
- Mar 09, 2025NOW Glycine 1 Lb. dropped by 7.5% to $15.99 at Amazon
- Mar 07, 2025EVLution Nutrition BCAA Energy 30 Servings (only Blue Raz) dropped by 9.1% to $19.99 at AllStarHealth
- Mar 01, 2025NOW GABA 100 Vcaps (only 500mg) dropped by 11% to $6.49 at Muscle and Strength
- Feb 24, 2025Xtend Original 90 Servings (only Fruit Punch) dropped by 24.6% to $48.99 at DPS Nutrition
- Feb 24, 2025Xtend Original 90 Servings (only Strawberry Kiwi Splash) dropped by 11.3% to $48.99 at DPS Nutrition
- Feb 22, 2025DAS Labs essentials - HMB 180 Capsules dropped by 25.2% to $14.95 at Amazon
- Feb 21, 2025NutraKey GABA 125 Grams dropped by 13.3% to $17.32 at Tiger Fitness
- Feb 18, 2025Country Life Gaba Relaxer 60 Tablets dropped by 26.2% to $13.49 at Best Price Nutrition
- Feb 16, 2025Fresh Supps Amino 30 Servings (only Shark Gummies) dropped by 11.1% to $39.99 at DPS Nutrition
- Feb 15, 2025Fresh Supps Amino 30 Servings (only Blueberry Pomegranate) dropped by 11.1% to $39.99 at DPS Nutrition
- Jan 10, 2025NOW GABA 90 Chewables dropped by 16.7% to $10.49 at AllStarHealth
- Jan 03, 2025Magnum Nutraceuticals H.M.B. Hard Muscle Builder 90 Capsules dropped by 15.5% to $38.00 at Suppz.com
- Nov 04, 2024MuscleTech Clear Muscle 84 Softgels dropped by 8.1% to $33.99 at Natural Body Inc
- Aug 23, 2024GHOST BCAA 30 Servings (only Lemon Crush, Sour Patch Kids Watermelon) dropped by 20% to $22.40 at Ghost Lifestyle
- Jun 09, 2024Double Wood Supplements Glycine 300 Capsules dropped by 46.9% to $19.95 at Walmart
- Jan 10, 2024PEScience Amino IV 60 Servings dropped by 9.1% to $42.50 at PEScience
- Jun 22, 2023PEScience Amino IV 30 Servings (only Orange Dreamsicle) dropped by 15% to $25.50 at PEScience
- May 17, 2023NutraBio Glycine 150 Grams dropped by 10% to $16.99 at NutraBio
- May 03, 2022Source Naturals GABA 90 Capsules dropped by 40% to $12.59 at VitaCost.com
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Amino Acid Reviews & Videos
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Apr 21, 2025Dileucine (DL185) Now Available at Unmatched Supplements -- Pure Muscle-Building Peptide #muscle
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Apr 18, 2025Setria Glutathione + PureWay-C Powers GHOST BASICS Antioxidant Formula #antioxidants #supplements
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Apr 18, 2025Podium FUSE 2025 -- NEW & IMPROVED Pre-Workout Formula #FUSE2025 #supplements #preworkout #fitness
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Apr 16, 2025Fresh Supps Creatine/HMB: Build AND Protect Muscle in Candy-Inspired Flavors #creatine #hmb #muscle
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Apr 16, 2025Reducing Malondialdehyde: Is Aldehyde Overload a Major Health Epidemic, and Can Cognizin Help?
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Apr 15, 2025PEScience Versa Energy Drink -- Perfect 125mg Caffeine #energydrink #drinkversa #supplements #focus
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Apr 14, 2025GRAPE GAINZ Are Here! New MuscleTech EuphoriQ V2 Pre Flavor
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Apr 14, 2025MitoPrime Ergothioneine: The Longevity Vitamin Backed By 3 Major Scientific Studies #healthspan
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Apr 10, 2025Big Things Can Come in Little Sizes | NNB's MitoPrime + NutriScience's SalidroPure! #supplements
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Apr 09, 2025New Cognizin and Setria Research Coming: Kyowa Hakko's Katie Emerson & Tony Miano | Episode 163
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Apr 08, 2025enfinity® Paraxanthine Makes Life Cider X the ULTIMATE ACV Energy Revolution! #Paraxanthine #acv
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Mar 31, 2025STOP CHOKING DOWN Apple Cider Vinegar - Try Life Cider X #LifeCiderX #acvbenefits #applecidervinegar
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Mar 26, 2025Ghost Basics Line Launches with Four Essential Supplements
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Mar 21, 2025Ai Energy Formula UPDATED Already! Jack Owoc's Latest Tweaks to His Nootropic Energy Drink
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Mar 18, 2025Titan Nutrition Stim-Rush: High-Energy Pre-Workout Delivers 333mg Caffeine + Focus Enhancement
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Mar 18, 2025Musclesport Pre Lean: Blending Essential Pre-Workout Staples w/ Old School & New School Innovations
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Mar 16, 2025Basic MASS: When Simple Nutrition Equals Serious Gains
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Mar 06, 2025GHOST Hydration v2 Returns: Enhanced Flavors & Sleek Design Elevate Hydration Game
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Mar 06, 2025Ghost Intra Lemon Lime: Fresh Citrus Flavor for Complete Workout Support
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Mar 06, 2025@ghostlifestyle just dropped Lemon Lime Intra and it's Full 9-EAA profile (not just BCAAs!) ...
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Feb 14, 2025MuscleSport Clean Whey Naturals Strawberry Ice Cream
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Feb 13, 2025MuscleSport Clean Whey Naturals Chocolate Ice Cream
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Feb 13, 2025Shoden Revolutionizes Ashwagandha with 35% Glycowithanolide Standard
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Feb 13, 2025NNB Nutrition's DL185 Dileucine Shows Significant Strength Gains in New PLOS ONE Study
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Feb 12, 2025Titan Nutrition KRE-EX Unrivaled Brings Back Full-Spectrum Pre-Workout Era
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Feb 11, 2025The Basic Essentials from Basic Supplements (Glutamine, Creatine, and BCAAs)
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Feb 11, 2025• Recovery = Results! Don’t Sleep on Recovery • Do you use Creatine? BCAA’s? Glutamine? All of...
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Feb 05, 2025Europa Sports Makes Fresh Start Under New Ownership with Fresh Supps Partnership
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Feb 03, 2025Modere's New Magnesium Blend for Optimal Performance
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Jan 29, 2025Enhanced Labs Shred Powers Your Cut with NeuroRush and CapsiBurn
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Jan 28, 2025Why Spoken Aminos + ATP Goes Beyond Basic Amino Acids
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Jan 28, 2025Amino acids are back but not like before Spoken Aminos + ATP adds PeakATP for stim-free energy...
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Jan 27, 2025Nugenix Perform: Intimate Vitality Formula with Nitrosigine
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Jan 27, 2025The surprising science of Nitrosigine. From gym pumps to intimate performance. Breaking down the...
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Jan 16, 2025Basic Supplements Goes Full Transparency with Third-Party Lab Test Results
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Jan 07, 2025AN Performance Pre: One Pre-Workout for All Training Types
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Jan 03, 2025NNB Nutrition's Brain Health Platform: The Future of Nootropic Beverages
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Dec 21, 2024ISSN Updates Position Stand on HMB
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Dec 21, 2024ISSN has updated its position stand on HMB and everyone should be noticing. Muscle building and...
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Dec 18, 2024Fresh Supps Unwraps Kringle Candy for Christmas 2024
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Dec 16, 2024AN Performance: Now Exclusive at The Vitamin Shoppe
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Dec 10, 2024Ghost Glow: Capsules vs. Powder – Which One Fits Your Routine?
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Dec 06, 2024The Power of Nitric Oxide: A Key to Healthy Aging and Vitality with Nitrosigine
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Dec 05, 2024Obvi Collagen Pre: A Skin-Protecting Pre-Workout Supplement with NeuroRush!
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Dec 03, 2024AN Performance Hydration: Applied Nutrition USA’s ATP-Powered Performance Supplement
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Nov 28, 2024Sensapure Flavors Launches Innovation Center & New 2024 Flavor Concepts
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Nov 23, 2024Xtend BCAAs Airheads Taste Like The Real Thing?
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Nov 22, 2024@drinkxtend BCAAs airheads taste like the real thing?
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Nov 20, 2024Introducing Mindvalley States: Supplements to Support Your State of Mind
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Nov 19, 2024Cody Reviews ABE Energy Drink Grape Soda
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