Everyone's had one of those nights: three hours of sleep before an early flight, a newborn who won't settle, a deadline that eats into your bedtime. A 2024 study found that a single high dose of creatine monohydrate partly offset the cognitive fog from sleep deprivation, with brain imaging to show why.
The catch? At that dose, purity matters. Nutristat Creatine uses Creapure® from AlzChem, the same German manufacturer behind the creatine used in the study. When you're taking 28g in one sitting instead of the standard 5g daily dose, the difference between 99.9% purity and generic 96% purity isn't trivial. Read the full breakdown of the research, the dosing protocol, and why sourcing matters when the dose gets serious.
Some days you want more protein but not another thick shake. PVL ISO CLEAAR is the answer, a clear, juice-like protein with 20g protein and 80 calories, headlined by LEUVATE+™ making its commercial debut.
This dairy-free formula delivers 12g whole protein from beef, pea, and fava sources, plus 8g free-form amino acids split between LEUVATE+™ and a conditionally essential amino acid blend. The result is a lighter, grab-and-go protein option that mixes clear in cold water with no blender required. Read the full breakdown to see how PVL's newest project stacks up.
NYNE debuts with NYNE Focus, a caffeine-free nootropic beverage built around 250mg of Cognizin® Citicoline and seven additional disclosed ingredients. Instead of caffeine, it uses paraxanthine for a cleaner stimulant experience alongside L-theanine, Zynamite® S, and other research-backed nootropics designed to support steady attention through a full workday.
The ready-to-drink formula comes in 12 fl oz cans with zero added sugar, zero artificial sweeteners, and a fully transparent label. For those managing long workdays or back-to-back focus sessions, NYNE Focus offers a single-can alternative to stacking multiple coffees or piecing together a nootropic regimen from powders and capsules.
New ex vivo data presented at ISSN 2026 shows Helaina's effera® human lactoferrin built a stronger gut barrier than bovine lactoferrin at every shared dose, and the effect was strongest when the gut was under inflammatory stress. The study tested doses ranging from 50mg to 1000mg per day using Cryptobiotix's SIFR® platform to model what happens after lactoferrin reaches the gut.
The standout finding: effera®'s lowest tested dose of just 50mg per day produced a stronger barrier response than either 100mg or 500mg of bovine lactoferrin, changing the cost equation for formulators. The ingredient also drove more short-chain fatty acid production and kept inflammatory markers below control levels across all doses. Read the full breakdown of the ISSN 2026 poster and what it means for gut health formulations.
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