Essential fatty acids (EFA) are healthy fats that the body needs but can't produce on its own. There are two fatty acids that are essential for human health, alpha-linolenic (also known as omega-3 fatty acids) and linoleic acid (omega-6).[1] The only way to get these nutrients is through a well-rounded diet.
Fish and fish oil supplements are the best sources of omega-3 fatty acids. Westerners tend to consume more omega-6s, found in poultry, eggs, and most vegetable oils, than omega-3s, which are abundant in fish and seafood sources. A diet low in omega-3s is thought to be a factor in the increased rate of heart disease in the U.S.
Omega-3 fatty acids
The omega-3 category consists of two sub-groups: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Consuming these healthy polyunsaturated fats (PUFAs) are known to help reduce high blood pressure and high cholesterol levels, both increased risk factors for developing heart disease.
Fish oil
Fish oil supplements contain the omega-3 fatty acids that are so important for human health. If you get enough in your diet from whole foods — fish, primarily — supplementation may not be needed. If you don't consume omega-3s two to three times a week, you may want to take a fish oil supplement.
One serving of most fish oil supplements is sufficient for providing the recommended daily allowance (RDA) of EPA and DHA combined.
Benefits
Fish oil helps reduce risk of coronary artery disease, cardiac arrhythmia, type 2 diabetes, and elevated serum triglycerides. It also decreases risk of mortality and helps with depressive mood disorders.[2, 3]
DHA
Docosahexaenoic acid (DHA) is beneficial for cognitive functions, neuromuscular control, and is the preferred omega-3 fatty acid for neural and retinal development.[4] Supplementing DHA with fish oil is a great way to maximize the benefits of both fatty acids.
EPA
Eicosapentaenoic acid (EHA) is credited for helping alleviate symptoms related to depressive mood disorders. The fatty acid also helps with sight and brain function. Taking EPA may slow the onset and progression of cognitive disorders, including Alzheimer's disease and dementia.[1, 8]
Studies demonstrate that fish oil supplementation provides physical and cognitive benefits throughout your life. Children benefit by the aid of brain and retinal development, and the elderly benefit by slowing deterioration of brain function — a normal part of the aging process.
Suggested supplementation
- To get your recommended dosage of EPA and DHA, we recommend taking a fish oil supplement, especially if your diet is not rich in seafood. NOW Foods produces a good EPA-only supplement — Super EPA. You can also try Carlson's EPA Gems.
Cod liver oil and krill oil
Cod liver oil supplements contain vitamins A and D, in addition to DHA and EPA. If you don't eat a lot of fruits and vegetables, and don't take a multivitamin, cod liver oil may be a good option for you.
Krill oil does not contain vitamins A or D. It was shown to be potentially more effective than other types of fish for boosting lipid metabolism in obese individuals.[10] Long-term consumption may increase fat loss for those who are overweight. Krill oil is much more potent for ridding the body of eicosanoids, which induce inflammation.[1] Low-grade chronic inflammation is a top heart disease factor in those who are otherwise healthy.
Try NOW Neptune Krill Oil or Jarrow Formulas' PhosphOmega Krill Oil.
Recommended dose
Healthy adults should get 500mg of fish oil daily (1:1 EPA to DHA ratio). Adults with heart disease should consume 1g each day, and those with high cholesterol and/or high blood pressure should take 3g to 4g.[17] The overall maximum dosage is 4g daily.
Omega-6 fatty acids
Omega-6 fatty acids are in vegetable oil, corn oil, soybean oil, nuts, and seeds. Most Americans tend to get their RDA of this fatty acid.[1]
Benefits
Omega-6 fatty acids help with brain health, particularly common aging disorders, heart health, and inflammation. The compound also helps build muscle.
Gamma linoleic acid (GLA)
Gamma linoleic acid (GLA) is a natural anti-inflammatory that helps relieve rheumatoid arthritis symptoms, reduces symptoms associated with eczema, and helps prevent cardiovascular illnesses.[12] GLA is an omega-6 fatty acid that can be synthesized in the body, but works better when supplemented in the diet.
Dosage varies by the condition GLA is used to treat:
Health condition | Recommended GLA dose |
---|---|
Skin conditions | 360mg to 750mg daily |
Pre-menstrual syndrome | 240mg to 320mg daily |
Rheumatoid arthritis | 750mg to 2.8g daily for 6 to 12 months |
Diabetic neuropathy | 480mg daily |
High blood pressure | 1.3g daily |
High cholesterol | Up to 2g daily[17] |
Side effects
Exceeding 2.8g daily can result in minor gastrointestinal discomfort (similar to fish oil consumption), though that subsides with consistent consumption.[17]
Black currant oil
Black currant oil is a popular, inexpensive supplement that contains GLA. The downside is that the concentration of GLA is small.
- We like NOW Black Currant Oil or Health From The Sun Black Currant Oil .
Borage oil
Borage oil containsone of the highest concentrations of GLA compared to other sources.
- NOW Borage Oil and Nature's Way EFA Gold Borage Oil are good sources of GLA.
Primrose oil
Primrose oil is a good source of GLA and is very popular for treating menstrual cramps.
- NOW Super Primrose or Jarrow Formulas Evening Primrose 1300 are good options.
References
- Higdon, J.; Linus Pauling Institute at Oregon State University; Essential Fatty Acids; updated January 2012
- Léon, H. et al.; BMJ; "Effect of fish oil on arrhythmias and mortality: a systematic review;" December2008
- Pin, K. S. et al.; European Neuropsychopharmacology; "Omega-3 fatty acids in major depressive disorder: A preliminary double-blind, placebo-controlled trial;" 2003
- Anderson, G. J. et al.; Pediatric Research; "Docosahexaenoic Acid Is the Preferred Dietary n-3 Fatty Acid for the Development of the Brain and Retina;" 1990
- Philbrick, D. J. et al.; The Journal of Nutrition; "Ingestion of fish oil or a derived n-3 fatty acid concentrate containing eicosapentaenoic acid (EPA) affects fatty acid compositions of individual phospholipids of rat brain, sciatic nerve and retina;"1987
- Martins, J. G.; Journal of the American College of Nutrition; "EPA but not DHA appears to be responsible for the efficacy of omega-3 long chain polyunsaturated fatty acid supplementation in depression: Evidence from a meta-analysis of randomized controlled trials;" October 2009
- AP, S.; Journal of the American College of Nutrition; "Omega-3 fatty acids in inflammation and autoimmune diseases;" December 2002
- Samieri C.; American Journal of Clinical Nutrition; "Low Plasma Eicosapentaenoic Acid and Depressive Symptomatology are Independent Predictors of Dementia Risk;" September 2008
- Penniston, K. L.; Tanumihardjo, S.A.; American Journal of Clinical Nutrition; "The acute and chronic toxic effects of vitamin A; American Society for Clinical Nutrition;" February 2006.
- Banni, S. et al.; Nutrition & Metabolism; Krill oil significantly decreases 2-arachidonoylglycerol plasma levels in obese subjects;" 2011
- Adam O., The Clinical Investigator; "Immediate and long range effects of the uptake of increased amounts of arachidonic acid;"1992
- Kapoor, R.; Gamma Linolenic Acid: A Natural Anti-inflammatory Agent—Part I; 2005.
- Henderson, K.; The Doctor's Prescription for Healthy Living;"A little bit of heaven from omega-7;" Volume 9, Number 6
- Brookshier, S.; The recommended levels of fish oil per day; Demand Media; 2014
- Pharma Nord; Gamma linoleic acid (GLA - Omega 6); 2006
- Natural Wellbeing; Omega 9; 2012
- Alt MD; Gamma linoleic acid; The Gale Group; 2008
- Villani, A. M. et al.; BMC Geriatrics; "Fish oil administration in older adults: is there potential for adverse events? A systematic review of the literature;" May 2013
- Claire Groden; Time Magazine; Hold The Salmon: Omega-3 Fatty Acids Linked to Higher Risk of Cancer; July 2013.
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- Feb 27, 2021NOW Krill & CoQ10 60 Softgels dropped by 12.1% to $22.56 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil 39 Softgels dropped by 11.1% to $8.24 at iHerb.com
- Feb 27, 2021Natural Factors RxOmega-3 240 Softgels dropped by 24.9% to $27.46 at iHerb.com
- Feb 27, 2021Doctor's Best Best DHA 500 from Calamari 60 Softgels dropped by 7.2% to $13.24 at iHerb.com
- Feb 27, 2021Doctor's Best Real Krill - Enhanced with DHA & EPA 60 Softgels dropped by 7.8% to $17.51 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil + D3 90 Softgels dropped by 11.1% to $9.74 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil 320 Softgels dropped by 19.9% to $18.68 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil 145 Softgels dropped by 11.0% to $8.64 at iHerb.com
- Feb 27, 2021Nature's Bounty Mini Fish Oil 90 Softgels (only 1290mg - Heart Health) dropped by 11.2% to $11.35 at iHerb.com
- Feb 27, 2021MuscleTech Platinum 100% Fish Oil 100 Softgels dropped by 20.0% to $6.37 at iHerb.com
- Feb 27, 2021Natural Factors RxOmega-3 120 Softgels (only 600mg EPA/DHA) dropped by 22.3% to $11.86 at iHerb.com
- Feb 27, 2021NOW Neptune Krill Oil 60 Softgels (only 1000mg) dropped by 6.3% to $24.06 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil 220 Softgels dropped by 11.0% to $13.33 at iHerb.com
- Feb 27, 2021Natural Factors RxOmega-3 8 Oz. dropped by 10.8% to $23.71 at iHerb.com
- Feb 27, 2021Natural Factors WomenSense - RxOmega-3 120 Softgels dropped by 18.8% to $11.86 at iHerb.com
- Feb 27, 2021NOW Super Omega EPA 240 Softgels dropped by 6.3% to $16.04 at iHerb.com
- Feb 27, 2021Nature's Bounty Fish Oil 90 Softgels (only 2400mg Heart Health) dropped by 11.1% to $11.93 at iHerb.com
- Feb 27, 2021NOW Evening Primrose Oil 120 Softgels dropped by 12.1% to $12.53 at iHerb.com
- Feb 27, 2021NOW Ultra Omega-3 180 Softgels dropped by 6.2% to $18.45 at iHerb.com
- Feb 26, 2021SAN Premium Fish Fats Gold 120 Softgels dropped by 25.4% to $10.73 at Amazon
- Feb 26, 2021Transparent Labs Krill Oil 60 Softgels dropped by 10.5% to $24.65 at Transparent Labs
- Feb 26, 2021Blackstone Labs Fish Oil 90 Softgels dropped by 16.7% to $18.75 at Best Price Nutrition
- Feb 25, 2021BioTrust OmegaKrill 5X 90 Softgels dropped by 8.3% to $44.00 at Amazon
- Feb 25, 2021Nutrex Lipo-6 CLA 45 Softgels dropped by 13.7% to $6.00 at Amazon
- Feb 24, 2021Core Nutritionals Omega 120 Softgels dropped by 23.5% to $19.89 at eBay.com
- Feb 23, 2021SportsResearch Omega-3 Triple Strength 180 Softgels dropped by 11.2% to $39.95 at Amazon
- Feb 23, 2021Wiley's Finest Wild Alaskan Fish Oil Vitamin K2 60 Softgels dropped by 7.7% to $28.04 at Vitamin Shoppe
- Feb 23, 2021Onnit Joint Oil 12 Oz. dropped by 11.0% to $26.39 at Vitamin Shoppe
- Feb 22, 2021Nature's Way EFAGold Evening Primrose Oil 100 Softgels dropped by 15.0% to $8.77 at VitaCost.com
- Feb 22, 2021NOW Black Currant Oil 100 Softgels (only 1000mg) dropped by 10.0% to $12.38 at VitaCost.com
- Feb 22, 2021NOW Omega-3 30 Softgels dropped by 9.9% to $1.92 at VitaCost.com
- Feb 22, 2021Optimum Nutrition Fish Oil Softgels 200 Softgels dropped by 10.9% to $12.48 at Vitamin Shoppe
- Feb 22, 2021Wiley's Finest Wild Alaskan Fish Oil Beginners DHA for Kids 4.23 Oz. dropped by 33.3% to $14.98 at Vitamin Shoppe
- Feb 21, 2021Flora Udo's Oil 3-6-9 Blend 17 Oz. dropped by 46.4% to $14.24 at eVitamins
- Feb 21, 2021Olympian Labs Omega-3 Fish Oils 120 Softgels (only Enteric Coated - 1000mg) dropped by 23.8% to $16.99 at Amazon
- Feb 20, 2021Nature's Bounty Mini Fish Oil 90 Softgels (only 1290mg - Odor-Less) dropped by 45.3% to $16.99 at Amazon
- Feb 19, 2021Ascenta NutraSea Hp 6.8 Oz. dropped by 13.1% to $35.20 at Amazon
- Feb 19, 2021Nutrex Lipo-6 CLA 90 Softgels dropped by 27.3% to $15.99 at Muscle and Strength
- Feb 17, 2021Vital Choice High Potency DHA BrainCare 180 Softgels dropped by 15.3% to $49.99 at eBay.com
- Feb 17, 2021Ascenta NutraSea Omega-3 Liquid Gels 60 Softgels dropped by 64.4% to $14.23 at Amazon
- Feb 16, 2021Flora Udo's Oil DHA 3-6-9 Blend 17 Oz. dropped by 52.4% to $12.00 at AllStarHealth
- Feb 12, 2021GAT Omega-3 90 Softgels dropped by 7.7% to $11.99 at DPS Nutrition
- Feb 10, 2021NutraBio Omega 3 Fish Oil 500 Softgels dropped by 7.4% to $24.99 at Suppz.com
- Feb 09, 2021Carlson Super Omega-3 Gems 300 Softgels dropped by 19.8% to $32.07 at eVitamins
- Feb 05, 2021Cellucor COR-Performance Fish Oil 90 Softgels dropped by 15.0% to $5.44 at eBay.com
- Feb 04, 2021NOW Neptune Krill Oil 120 Softgels (only 1000mg) dropped by 10.4% to $44.78 at DPS Nutrition
- Feb 03, 2021Universal Animal Omega 30 Packs dropped by 37.5% to $31.95 at eBay.com
- Feb 01, 2021Health From The Sun Total EFA 16 Oz. dropped by 11.4% to $18.89 at AllStarHealth
- Jan 31, 2021Ascenta NutraSea Omega-3 6.8 Oz. (only Lemon -1250 EPA+DHA) dropped by 18.3% to $20.42 at iHerb.com
- Jan 25, 2021Source Naturals ArcticPure DHA 120 Softgels dropped by 23.4% to $22.98 at A1 Supplements
- Jan 25, 2021Health From The Sun Borage Oil 60 Softgels (only 1000mg) dropped by 13.7% to $15.00 at AllStarHealth
- Jan 18, 2021Schiff MegaRed 30 Softgels (only 353mg (Joint Care)) dropped by 19.9% to $30.39 at VitaCost.com
- Jan 18, 2021Minami Nutrition Vegan DHA 60 Softgels dropped by 22.4% to $24.99 at AllStarHealth
- Jan 18, 2021Nordic Naturals Ultimate Omega Liquid 8 Oz. dropped by 17.4% to $48.00 at AllStarHealth
- Jan 06, 2021Revive MD Omega 3 60 Softgels dropped by 6.6% to $28.00 at ReviveSups.com
- Jan 04, 2021Carlson Norwegian Salmon Oil Complete 240 Softgels (only 700mg) dropped by 32.7% to $34.99 at AllStarHealth
- Jan 04, 2021Carlson Baby’s DHA 2 Oz. dropped by 29.5% to $10.49 at AllStarHealth
- Jan 02, 2021NutraOne OmegaOne 90 Capsules dropped by 6.7% to $17.50 at eBay.com
- Dec 28, 2020New Chapter Wholemega 180 Softgels (only 1000mg) dropped by 9.7% to $43.18 at Best Price Nutrition
- Dec 27, 2020Carlson Elite Omega-3 Gems 180 Softgels dropped by 46.2% to $26.52 at iHerb.com
- Dec 21, 2020Carlson Cod Liver Oil Gems 100 Softgels (only Super 1000mg) dropped by 19.4% to $12.08 at iHerb.com
- Dec 21, 2020Health From The Sun Evening Primrose Oil 90 Softgels dropped by 41.3% to $15.50 at eVitamins
- Dec 18, 2020Blue Star Nutraceuticals Omega Blue 90 Softgels dropped by 67.5% to $12.99 at eBay.com
- Dec 14, 2020CTD Sports Omegathin 180 Softgels dropped by 20.6% to $21.42 at Best Price Nutrition
- Dec 07, 2020Udo's Choice DHA Oil Blend 17 Oz. dropped by 36.1% to $22.99 at AllStarHealth
- Nov 29, 2020Udo's Choice 3-6-9 Oil Blend 90 Vegetarian Softgels dropped by 14.2% to $12.00 at AllStarHealth
- Nov 21, 2020Nordic Naturals Complete Omega 60 Softgels dropped by 31.2% to $9.49 at Vitamin World
- Nov 19, 2020SNS X-Gels 100 Softgels dropped by 7.0% to $31.96 at DPS Nutrition
- Nov 09, 2020Body First DHA 120 Softgels dropped by 15.7% to $8.00 at AllStarHealth
- Oct 26, 2020Health From The Sun Evening Primrose Oil 60 1300mg Softgels dropped by 38.1% to $7.99 at AllStarHealth
- Oct 26, 2020Natrol Omega 3-6-9 Complex 90 Softgels dropped by 21.8% to $7.49 at AllStarHealth
- Oct 13, 2020Coromega Omega 3 Squeeze 120 Packets dropped by 20.0% to $31.00 at VitaCost.com
- Oct 12, 2020American Health Evening Primrose Oil 200 Softgels dropped by 18.5% to $8.65 at AllStarHealth
- Sep 30, 2020Carlson The Very Finest Fish Oil 150 Softgels (only Orange Flavor) dropped by 10.7% to $22.32 at VitaCost.com
- Sep 21, 2020Nordic Naturals Arctic Cod Liver Oil 8 Oz. (only Unflavored) dropped by 11.4% to $19.99 at AllStarHealth
- Sep 12, 2020Vital Choice Wild Sockeye Salmon Oil + Vitamin D3 6 Bottles (only 3000 IU D3 (180 SG)) dropped by 51.3% to $109.00 at Vital Choice
- Sep 12, 2020Vital Choice Wild Sockeye Salmon Oil + Vitamin D3 3 Bottles (only 3000 IU D3 (180 SG)) dropped by 50.8% to $59.00 at Vital Choice
- Sep 09, 2020Nordic Naturals ProOmega-D 60 Softgels dropped by 68.8% to $23.38 at iHerb.com
- Sep 07, 2020American Health Evening Primrose Oil 100 Softgels dropped by 9.0% to $8.52 at VitaCost.com
- Sep 07, 2020Health From The Sun Black Currant Oil 90 Softgels dropped by 21.5% to $16.49 at AllStarHealth
- Sep 07, 2020American Health Evening Primrose Oil 120 Softgels dropped by 30.4% to $9.39 at AllStarHealth
- Sep 07, 2020Nordic Naturals EPA 60 Softgels dropped by 8.3% to $21.99 at AllStarHealth
- Sep 07, 2020Nordic Naturals EPA Xtra 60 Softgels dropped by 9.4% to $28.99 at AllStarHealth
- Sep 07, 2020Nordic Naturals Arctic Cod Liver Oil 90 Softgels dropped by 6.1% to $16.49 at AllStarHealth
- Sep 06, 2020Natrol Omega 3-6-9 Complex 60 Softgels (only Lemon - 1200mg) dropped by 12.1% to $8.99 at VitaCost.com
- Sep 01, 2020Nordic Naturals DHA 180 Softgels dropped by 8.8% to $36.49 at AllStarHealth
- Aug 24, 2020Nordic Naturals Prenatal DHA 60 Softgels dropped by 19.3% to $28.22 at iHerb.com
- Aug 10, 2020Coromega Omega 3+D Squeeze 30 Packets (only Tropical Orange) dropped by 8.0% to $13.42 at iHerb.com
- Aug 09, 2020RSP Fish Oil 120 Softgels dropped by 15.6% to $15.18 at iHerb.com
- Jul 12, 2020MRM Smart Blend 120 Softgels dropped by 6.2% to $14.25 at AllStarHealth
- Jul 05, 2020Barlean's Total Omega 3-6-9 90 Softgels dropped by 11.1% to $20.82 at VitaCost.com
- Jun 29, 2020Carlson Norwegian Salmon Oil 300 Softgels (only 500mg - Omega-3s) dropped by 34.9% to $27.99 at AllStarHealth
- Jun 15, 2020Deva Nutrition Vegan Omega-3 DHA-EPA 90 Vegetarian Softgels dropped by 11.0% to $16.89 at AllStarHealth
- Jun 15, 2020Health From The Sun 100% Vegetarian Evening Primrose Oil 90 Softgels dropped by 21.1% to $14.35 at AllStarHealth
- Jun 15, 2020Olympian Labs Evening Primrose Oil 90 Softgels dropped by 20.6% to $12.96 at eVitamins
- Jun 15, 2020Source Naturals NKO 30 Softgels (only 500mg) dropped by 27.1% to $13.29 at eVitamins
- Jun 04, 2020Natrol Omega-3 Krill Oil 30 Softgels (only 1000 mg) dropped by 37.5% to $14.99 at AllStarHealth
- May 22, 2020Carlson The Very Finest Fish Oil 6.7 Oz. (only Orange Flavor) dropped by 12.4% to $20.14 at eVitamins
- Apr 27, 2020Source Naturals ArcticPure Omega-3 Fish Oil 30 Softgels (only 850mg) dropped by 16.7% to $6.64 at eVitamins
- Apr 27, 2020Source Naturals ArcticPure Omega-3 Fish Oil 60 Softgels (only 850mg) dropped by 23.2% to $10.48 at eVitamins
- Apr 27, 2020Udo's Choice 3-6-9 Oil Blend 17 Oz. dropped by 8.0% to $22.99 at AllStarHealth
- Apr 27, 2020Nordic Naturals Complete Omega 8 Oz. dropped by 33.2% to $15.30 at eVitamins
- Apr 08, 2020Schiff MegaRed 80 Softgels (only 500mg) dropped by 15.6% to $32.99 at VitaCost.com
- Feb 28, 2020Carlson Super DHA Gems 60 Softgels dropped by 20.8% to $14.99 at AllStarHealth
- Jan 16, 2020Udo's Choice High Lignan 3-6-9 Blend 17 Oz. dropped by 34.6% to $16.99 at AllStarHealth
- Oct 24, 2019Nordic Naturals Ultimate Omega 60 Softgels (only Strawberry (Mini) - 650mg) dropped by 19.3% to $23.99 at AllStarHealth
- Sep 16, 2019Nordic Naturals Arctic Cod Liver Oil 8 Oz. (only Strawberry) dropped by 7.0% to $19.99 at AllStarHealth
- Apr 04, 2019Minami Nutrition MorEPA Platinum 60 Softgels dropped by 17.3% to $32.99 at AllStarHealth
- Apr 04, 2019Carlson Norwegian Salmon Oil Complete 180 Softgels dropped by 29.7% to $19.99 at AllStarHealth
- Apr 04, 2019Nordic Naturals Arctic Cod Liver Oil 180 Softgels dropped by 7.6% to $32.79 at AllStarHealth
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