Probiotics, which means "for life," are live bacteria that help maintain the balance of intestinal organisms. About 400 probiotics fight to hinder dangerous bacteria and keep the digestive system healthy. [1] They are similar to organisms that are found naturally in the digestive tract. When taken in the proper amounts, probiotics may provide a variety of health benefits.[2]
Types of Probiotics
Some examples of probiotics that are naturally found in your body are:
Acidophilus
This is a group of probiotics that aids digestion.
Lactobacillus Acidophilus (L. Acidophilus): This bacteria is mostly found in the intestines, mouth and vagina. It helps balance the body's pH, keeping it at an acidic level, which can hinder the spread of harmful bacteria. Yogurt and fermented soy are good sources of L. acidophilus. It's available as a supplement as well, including pill, powder, and liquid forms.[7, 8, 23]
Lactobacillus Bulgaricus (L. Bulgaricus): This bacteria is found in the digestive tract -- intestines and stomach. It helps maintain acidic pH levels to reduce unhealthy bacteria levels, boost immunity, and block pathogen adhesion sites in the intestinal mucous lining. Sources include Bulgarian yogurt and Swiss cheese. It's also available as a supplement in capsule form.[18]
Lactobacillus Casei (L. Casei): This bacteria is found in the mouth and intestines. It helps prevent diarrhea and inflammation, depending on the strain, by controlling the spread of harmful bacteria while also encouraging the growth of healthy bacteria. Sources include yogurt, fermented green olives and cheese.[19]
Lactobacillus Rhamnosus (L. Rhamnosus): This bacteria is found in the intestines. It facilitates healthy bacterial growth, eliminates and interferes with the growth of harmful bacteria. Supplements are available in pill, suppository and liquid forms.[24]
Lactobacillus Reuteri (L. Reuteri): This bacteria is found in the intestines of mammals and birds -- and only some humans. It can help relieve certain conditions, including colic, acute diarrhea, IBS and eczema. It also hinders E. coli bacteria growth. Sources include milk, meat and supplements.[20].
Bifidobacteria
L. bifidus is a group of bacteria found in the intestines. It can also grow in a lab. Bifidobacteria can be taken to help restore healthy bacteria lost due to intestinal problems caused by illness or eliminated by certain medications. It's available as a supplement in a variety of forms, including pill, powder and fermented milk.[16]
Sub-strains of Bifidobacteria include:
Bifidobacteria can be taken to help restore healthy bacteria lost due to intestinal problems caused by illness or eliminated by certain medications.
Bifidobacterium Animalis (B. Animalis): This bacteria, found in human and animal intestines, promotes healthy digestion and may be helpful in the treatment of certain types of colitis. Yogurt provides a good source of B. animalis.[25]
Bifidobacterium Breve (B. Breve): This bacteria, found in the lower digestive tract, competes well with other bacteria. Some people have plenty of B. breve, but not everyone, so supplementation may be necessary to bring levels up. Like L. reuteri, B. breve can hinder E. coli as well as diarrhea and gas.[21]
Bifidobacterium Infantis (B. Infantis): This bacteria is found in the intestines. Acid produced by B. infantis may hinder harmful bacteria growth in the colon. Sources include cheese and yogurt.[22]
Saccharomyces Boulardii
This probiotic is found in the intestinal tract. It is available for purchase as a freeze-dried yeast. S. boulardii can help prevent and treat gastrointestinal disorders.[26]
Probiotics and special populations
Children: Probiotics may help treat a variety of health problems. Efficacy depends on the disease, strain of the probiotic and dosage. They appear to work effectively on:[5, 10, 11, 12, 14]
Digestive disorders
Gastrointestinal tract infections
Antibiotic-associated diarrhea (Prevention, not treating. More research needed)
Necrotizing enterocolitis (Death of intestinal tissue in very low birth weight babies)
Constipation (Research is mixed)
Atopic dermatitis
Probiotics don't seem to help children experiencing:[12]
Colic
Irritable bowel syndrome
Crohn's disease
Allergies
Some types of yogurt are a good source of probiotics for children.[13]
Athletes: Studies fail to show any potentially positive effects of probiotics on athletic performance, but they may provide secondary health benefits including:[6]
Healthy gastrointestinal tract maintenance
Quicker post-exercise recovery
Boosted immunity
Uses, benefits, and effectiveness
Probiotics have many uses and benefits, but they vary according to type and strain. Some uses include:
Diarrhea prevention and treatment (Strong evidence)[1, 9]
Digestive tract infection prevention[1]
Respiratory tract infections[4]
Vaginal yeast infection treatment and prevention[9]
Irritable bowel syndrome (Studies ongoing)[1]
Urinary tract infections in women (Effective) [4]
Inflammation control (Inflammatory bowel disease, for example, Crohn's disease. More studies are needed)[1, 3, 4]
Intestinal infection treatment [9]
May ease side effects of Helicobacteria pylori (H. pylori) treatment. (This bacteria causes most stomach ulcers. More studies needed.)[3, 14]
Tooth decay prevention[3]
Cold/flu prevention or reduction of severity[9]
Probiotics are being studied for their potential use in colon cancer, obesity, skin infection treatment, and cholesterol reduction.[1, 3]
Specific probiotics and the diseases they may help:
Immune system regulation
Bifidobacterium lactis HN019
Lactobacillus reuteri ATCC55730
Lactobacillus rhamnosus GG (LGG)
Lactobacillus casei DN-114001
Bifidobacterium lactis Bb-12
Antibiotic-Associated Diarrhea
S cerevisiae (S. boulardi)
Lactobacillus rhamnosus GG (LGG)
Lactobacillus casei DN-114001
Lactobacillus acidophilus CL 1285 plus Lactobacillus casei Lbc80r
Bacterial Vaginosis
Lactobacilli
Safety concerns and side effects
Probiotics may not be safe for the elderly, young children, people who are critically ill, people with gastrointestinal disorders, short bowel syndrome, indwelling venous catheters, weakened immunity or high fever. Ask your doctor before starting probiotic therapy.[1, 2, 3, 5, 8]
Although probiotics don't usually have many side effects, some that could occur are flatulence, abdominal cramps and septicemia (blood infection). Effects of long-term use are unknown. Use with care. Take only as directed.[3, 14]
Avoid use if you are allergic to milk.[8]
Tell your medical team all the medications you are taking, including those that are complementary and alternative.[3]
Do not use different forms of Lactobacillus Acidophilus together unless prescribed by a doctor.[7]
Bifidobacteria may cause bloating and gas.[16]
Store lactobacillus acidophilus in a dry, dark, cool place.[7]
Probiotic ingredients should be clearly marked on the package. Only use products you are familiar with and trust.[4]
Probiotics allergy protection benefits are not clear in regard to use in children.[12]
Although Lactobacillus GG has been deemed safe for use during pregnancy, to be safe, do not take lactobacillus acidophilus if you are pregnant or breast-feeding without first consulting your doctor.[7,8]
Do not take Lactobacillus Acidophilus if you have health problems, allergies, or take medications or supplements without first talking to your doctor.[7]
Do not give a child probiotics without first consulting the child's pediatrician.[7]
Risk of sepsis from Lactobacillus Rhamnosus GG and Bifidobacterium sp. is low.[14]
Bifidobacteria is safe for adults and children if used properly.[16]
Signs of allergic reaction to Lactobacillus Acidophilus include hives, swollen face, tongue, throat and lips, and breathing difficulty.[7]
Infant formulas containing probiotics seem to be safe for healthy babies but research doesn't show benefits.[12]
Recommended dosage
Follow directions as indicated on the label. In general, 5 to 10 billion colony-forming units (CFU's) per day for children and 10 to 20 billion daily for adults are recommended. Consult your doctor for dosages recommended for your specific situation.[14, 16]
Interactions
Antibiotics: Antibiotics may reduce the effectiveness of bifidobacteria. Take antibiotics at least two hours before or after bifidobacteria.[16]
Buying probiotics
Find the best deals on probiotics check out PricePlow's buying guide Our price comparisons make it easy to find the lowest price from any health store on the web. You can save from 30 to 50% by buying through the listings on this page versus your local retail store.
What Is the best probiotic
It depends on many factors. Strains vary even within the same species. They're also used for completely different health issues and it depends on your body's chemistry.
Each person may react to a specific probiotic strain differently.
Choose probiotics from trusted manufacturers and brands that are known to be effective for your particular needs. Use what works for you. [3,15]
That said, you may want to try Nature's Way Primadophilus. Products are guaranteed pure, potent and effective. On top of that, they offer a variety of high-quality probiotics for different populations, including different age groups and vegetarians.[17]
Considerations
Probiotics are regulated as foods, not medications.[1]
Because probiotics are marketed as dietary supplements, they do not require FDA approval. But probiotics marketed as a treatment for a specific condition need FDA approval.[12]
The FDA hasn't approved any specific probiotic health claims.[2]
There is not much scientific evidence to confirm the use and benefits of many probiotics.[3]
The number of live organisms in probiotic products may vary from what is listed on the label or advertised.[5]
Choose probiotics that are marked viable "through the end of shelf life."[15]
Just because a product has more live probiotics that doesn't mean it's better.[15]
References
- WebMD; "Probiotics - Topic Overview;" Updated 2011
- Elaine Magee, MPH, RD; WebMD; "5 Things You Should Know About Probiotic Products;" Reviewed 2009
- National Institutes of Health; National Center for Complementary and Alternative Medicine; Get the Facts;"Oral Probiotics: An Introduction;" Updated 2012
- The Harvard Medical School Family Health Guide; "Health Benefits of Taking Probiotics;" Updated 2005Journal of Pediatric Gastroenterology and Nutrition"Clinical Efficacy of Probiotics: Review of the Evidence with Focus on Children;" 2006
- Andrew W. Nichols, MD; Current Sports Medicine Reports; "Probiotics and Athletic Performance: A Systematic Review;" 2007
- Drugs.com; "Acidophilus Extra Strength;"
- Mayo Clinic; "Acidophilus (Lactobacillus acidophilus)"Katherine Zeratsky; RD; Mayo Clinic; "Is It Important to Include Probiotics and Prebiotics in a Healthy Diet?;" 2011
- ScienceDaily; "Probiotic-Derived Treatment Offers New Hope for Premature Babies;" 2013
- Tabbers MM, et. al.; Nutrition Journal; "Is Bifidobacterium Breve Effective in the Treatment of Childhood Constipation? Results from a Pilot Study;" January 2011
- Katrina Woznicki; WebMD; "Children May Benefit From Probiotics, Prebiotics;" November 2010
- Gina Shaw; WebMD; "A Nutritionist Speaks: How to Promote Your Child's Digestive Health;" Gina Shaw; February 2012
- Benjamin Kligler, MD, Andreas Cohrssen, MD; American Academy of Family Physician; "Probiotics;" November 2008
- California Dairy Research Foundation; "Frequently Asked Questions & Consumer Information;"
- MedlinePlus; "Bifidobacteria;" December 2012
- Nature's Way; "Primadophilus"
- Probiotic.org; "Lactobacillus Bugaricus"
- Probiotic.org; "Lactobacillus Casei"
- Probiotic.org; "Lactobacillus Reuteri"
- Probiotic.org; "Bifidobacterium Breve"
- Probiotic.org; "Bifidobacterium Infantis"
- Probiotic.org; "Acidophilus"
- Probiotic.org; "Lactobacillus Rhamnosus"
- Probiotic.org; "Bifidobacterium Animalis"
- Probiotic.org; "Saccharomyces Boulardii"
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Probiotic Price Alerts
The following price alerts are still active:
- Jun 08, 2023Swanson Dr. Stephen Langer's Ultimate 16 Strain Probiotic with FOS 60 Vcaps dropped by 31.2% to $11.79 at Amazon
- Jun 08, 2023Garden of Life Dr. Formulated Probiotics - Immune Plus 30 Vcaps dropped by 10.2% to $43.99 at Amazon
- Jun 08, 2023Jarrow Formulas Jarro-Dophilus EPS 30 Vcaps (only 50 Billion) dropped by 13.1% to $31.52 at Amazon
- Jun 07, 2023Swanson Lactobacillus Gasseri 60 Vcaps dropped by 32.3% to $8.73 at iHerb.com
- Jun 07, 2023Swanson Ultimate Probiotic Formula 30 Vcaps dropped by 40% to $11.05 at iHerb.com
- Jun 05, 2023Force Factor ProbioSlim 60 Capsules dropped by 13.3% to $12.99 at Muscle and Strength
- Jun 04, 2023Jarrow Formulas Fem-Dophilus Advanced 30 Vcaps dropped by 7.7% to $32.32 at Amazon
- Jun 01, 2023Jarrow Formulas Probiotic Duo 90 Gummies dropped by 15% to $16.30 at VitaCost.com
- Jun 01, 2023Jarrow Formulas Probiotic + Immune 60 Gummies dropped by 15% to $14.02 at VitaCost.com
- May 31, 2023Flora Udo's Choice Advanced Adult's Probiotic 60 Vcaps dropped by 7.8% to $36.89 at Best Price Nutrition
- May 27, 2023Nutrex Lipo-6 Black Probiotic 30 Capsules dropped by 11.8% to $14.99 at Muscle and Strength
- May 26, 2023KAL Acidophilus Probiotic-4 250 Vcaps dropped by 25.9% to $12.59 at Best Price Nutrition
- May 23, 2023Solaray Vegan Acidophilus 60 Vcaps dropped by 13.9% to $8.99 at Best Price Nutrition
- May 23, 2023EVLution Nutrition Probiotic 60 Vcaps dropped by 20.8% to $11.99 at Walmart
- May 23, 2023Garden of Life Primal Defense 216 Vcaps dropped by 14.3% to $56.99 at MySupplementStore
- May 23, 2023NOW Acidophilus Two Billion 100 Vcaps dropped by 17.8% to $5.58 at MySupplementStore
- May 23, 2023Garden of Life Primal Defense 180 Vcaps dropped by 6.1% to $61.84 at MySupplementStore
- May 23, 2023NOW Probiotic Defense 90 Vcaps dropped by 8.8% to $13.49 at Best Price Nutrition
- May 23, 2023Garden of Life Dr. Formulated Probiotics - Urinary Tract+ 60 Vcaps dropped by 10.8% to $30.23 at Best Price Nutrition
- May 23, 2023Garden of Life Raw Probiotics - 5-Day Max Care 2.4 Oz. dropped by 10% to $28.34 at Best Price Nutrition
- May 23, 2023Garden of Life Vitamin Code Raw Kombucha 60 Vcaps dropped by 10.4% to $22.04 at Best Price Nutrition
- May 23, 2023NOW OralBiotic 60 Lozenges dropped by 11.6% to $10.79 at Best Price Nutrition
- May 23, 2023Garden of Life Primal Defense Ultra 216 Vcaps dropped by 9.8% to $62.99 at Best Price Nutrition
- May 22, 2023Jarrow Formulas Saccharomyces Boulardii 90 Vcaps dropped by 8.3% to $26.99 at Best Price Nutrition
- May 22, 2023Garden of Life Primal Defense 81 Grams dropped by 8.1% to $34.01 at Best Price Nutrition
- May 22, 2023Garden of Life Dr. Formulated Probiotics - Once Daily Men's 30 Vcaps dropped by 15.1% to $20.78 at Best Price Nutrition
- May 22, 2023Garden of Life Raw Probiotics - Colon Care 30 Vcaps dropped by 8.3% to $28.34 at Best Price Nutrition
- May 20, 2023NOW NutraFlora FOS Powder 4 Oz. dropped by 10% to $10.21 at iHerb.com
- May 15, 2023Olly Extra Strength Probiotic 50 Gummies dropped by 16.7% to $14.99 at Vitamin Shoppe
- May 14, 2023Renew Life Ultimate Flora Women's Care Probiotic 30 Vcaps (only 15 Billion) dropped by 17.7% to $14.39 at AllStarHealth
- May 11, 2023TruWild Kombucha 20 Servings dropped by 7% to $29.75 at eBay.com
- May 10, 2023Nature's Bounty Probiotic - Controlled Delivery 30 Capsules (only 2 Billion Active & 6 Probiotic Strains) dropped by 6.2% to $13.14 at MyOTCstore.com
- May 04, 2023Jarrow Formulas Yum-Yum Dophilus 120 Chewables dropped by 22.3% to $14.95 at Amazon
- Apr 22, 2023Swanson FemFlora Probiotic For Women 60 Capsules dropped by 15% to $11.39 at iHerb.com
- Apr 18, 2023Jarrow Formulas Saccharomyces Boulardii plus MOS 90 Vcaps dropped by 20.8% to $17.89 at AllStarHealth
- Apr 14, 2023Olly Probiotic 80 Gummies dropped by 13.7% to $16.71 at iHerb.com
- Apr 10, 2023Kaged Pro-Biotic 30 Vcaps dropped by 60% to $29.99 at Wegmans
- Apr 09, 2023Nordic Naturals Nordic Flora Probiotic - Women's Balance 30 Capsules dropped by 38.9% to $40.34 at iHerb.com
- Apr 02, 2023Natural Factors Acidophilus & Bifidus 180 Capsules (only 10 Billion Active Cells) dropped by 9.7% to $23.99 at AllStarHealth
- Mar 11, 2023Garden of Life baby - pro-biotic 1.9 Oz. dropped by 7.6% to $17.28 at iHerb.com
- Mar 10, 2023Jarrow Formulas Fem-Dophilus 60 Vcaps (only 1 Billion CFU) dropped by 13% to $22.99 at AllStarHealth
- Mar 05, 2023Udo's Choice Adult's Probiotic 120 Capsules dropped by 21.8% to $28.00 at AllStarHealth
- Feb 24, 2023Jarrow Formulas Baby's Jarro-Dophilus 2.5 Oz. (only +GOS - Powder) dropped by 34.8% to $14.64 at VitaCost.com
- Feb 19, 2023Renew Life Ultimate Flora Ultimate Care Probiotic 30 Vcaps (only 150 Billion) dropped by 10.9% to $48.99 at AllStarHealth
- Feb 10, 2023NOW Acidophilus Two Billion 250 Capsules dropped by 7.1% to $14.49 at VitaCost.com
- Feb 06, 2023Schiff Digestive Advantage - Lactose Defense Formula 96 Capsules dropped by 8.2% to $22.99 at VitaCost.com
- Jan 12, 2023Jarrow Formulas Saccharomyces Boulardii plus MOS 180 Vcaps dropped by 11.3% to $32.99 at AllStarHealth
- Jan 12, 2023Jarrow Formulas Fem-Dophilus 60 Vcaps (only 5 Billion CFU) dropped by 17.6% to $22.99 at AllStarHealth
- Jan 07, 2023Nature's Bounty Probiotic GX 25 Capsules dropped by 28.4% to $19.48 at MyOTCstore.com
- Dec 19, 2022Flora Toddler's Probiotic 2.64 Oz. dropped by 9.2% to $21.99 at VitaCost.com
- Sep 30, 2022Doctor's Best Probiotic 30 Vcaps dropped by 11.3% to $12.32 at AllStarHealth
- Sep 17, 2022Flora Udo's Choice Super 8 Hi-Potency Probiotic 30 Capsules dropped by 8.7% to $21.99 at VitaCost.com
- Sep 06, 2022Vitacost Probiotic with Vitamin D3 60 Tablets dropped by 7.4% to $9.99 at VitaCost.com
- Aug 22, 2022Health Plus Probiotic Fiber 30 Capsules dropped by 7.1% to $12.99 at AllStarHealth
- Jun 22, 2022KAL Dinosaurs Dino-Dophilus 60 Chewables dropped by 40.1% to $7.49 at AllStarHealth
- Jun 11, 2022Nature's Way Fortify Optima Probiotic 30 Vcaps (only Advanced Care - 100 Billion) dropped by 28.4% to $31.99 at AllStarHealth
- Mar 29, 2022NOW Clinical GI Probiotic 60 Vcaps dropped by 10.4% to $12.99 at AllStarHealth
- Feb 21, 2022NOW Probiotic-10 60 Vcaps dropped by 15.3% to $34.99 at AllStarHealth
- Jan 21, 2022NOW Probiotic-10 30 Vcaps (only 100 Billion) dropped by 13% to $19.39 at AllStarHealth
- Sep 10, 2021NOW Probiotic-10 & Bifido Boost 90 Vcaps dropped by 11.3% to $13.99 at AllStarHealth
- Mar 01, 2021NOW Respiratory Care Probiotic 60 Vcaps dropped by 7.8% to $13.79 at AllStarHealth
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