Rhodiola rosea is a unique plant that grows naturally in cold regions such as Sweden and Russia. Historically, the plant has been used as an adaptogen, which is a compound that the body utilizes to neutralize hostile physical, chemical or biological stressors. By providing resistance to stressors, Rhodiola rosea helps balance brain chemistry.
Adaptogens such as Rhodiola have been shown to "Increase the availability of energy during the day, reduce stressed feelings, increase endurance, and increase mental alertness."
Thus, Rhodiola rosea makes for a beneficial addition to nearly anyone's health regimen, and we are major fans of it on this site.
Benefits of Rhodiola rosea
In the traditional medical systems of Eastern Europe and Asia, Rhodiola rosea extracts purportedly
- Stimulate the nervous system,
- Has demonstrated anti-depressive activity,
- Enhance work performance,
- Ameliorate fatigue, and
- Prevent high altitude sickness
Having been intensively studied in Russia and Scandanavia for more than 43 years, many human and animal studies support the aforementioned claims. Here are a list of proven benefits.
Central nervous system modulation
In animal studies, small and medium doses confer a stimulating effect such as "lengthening the time mice could swim and remain on vertical perches to the limit of their abilities." Larger doses, though, show sedative effects. The effects of Rhodiola on the CNS are twofold:
It stimulates the neurotransmitter systems for norepinephrine, dopamine, serotonin and short-term acetylcholine activation.
It enhances the effects of these neurotransmitters via increased permeability of the blood brain barrier (BBB), allowing precursors to dopamine and serotonin to enter the brain more easily.
Rhodiola rosea extracts are known to stimulate the nervous system, may alleviate symptoms of depression, enhance work performance, ameliorate fatigue, and prevent high altitude sickness.
Releasing the neurotransmitters dopamine, serotonin and norepinephrine activates the cerebral cortex and limbic system, thus enhancing the cognitive functions of the cerebral cortex (thinking, analyzing, evaluating, calculating and planning).
By enhancing the cholinergic system, Rhodiola improves memory storage within the limbic system (hippocampus and amygdala). Acetylcholine "contribute[s] to the memory function via pathways ascending from the memory storage in the limbic system to various areas of the cerebral cortex (memory retrieval)."
Resistance to stress
Stress should be the paramount enemy on every health buff's list, and Rhodiola has produced positive effects by quelling the body's natural stress response and potent antioxidant activity.
The serotonin system is imperative for stress response, adaptation to novel environmental conditions and tolerance of hypoxia (oxygen deprivation) -- many stressors decrease serotonin levels in the hypothalamus.
Extracts of Rhodiola may increase resistance to stress because they elevate serotonin in the hypothalamus and midbrain.
A sudden increase in opioid and catecholamine (dopamine, norepinephrine) levels occur in response to stress, which obstruct normal brain function and can cause heart damage.
"R. rosea moderates the release of opioid peptides that occurs as part of the HPA axis response to stress....while allowing a more moderate release that increases stress tolerance without damaging the central nervous system or the cardiovascular system."
According to multiple studies, acute doses of Rhodiola extract before acute stress "produces favorable results and prevents stress-induced disruptions in function and performance." Because stressful situations usually occur randomly, Rhodiola could prove very useful because it does not require weeks of preemptive supplementation. 
Physical work capacity
Rhodiola has been shown to increase work capacity, reduce recovery time after exercise and enhance endurance.
One study on master level skiers who competed in a 20-km race while carrying rifles and shooting targets found that "The group receiving R. rosea had a statistically significant increase in shooting accuracy, less arm tremor, and better coordination, and the heart rate was 104% to 106% of baseline; whereas in the placebo group, the heart rate was about 129% of baseline."
Animal studies suggest that improvements in work capacity and endurance are due to Rhodiola increasing the essential energy metabolites adenosine triphosphate (ATP) and creatine phosphate (CP) in the muscle and brain mitochondria of mice during intensive exercise.
The same study elucidates how Rhodiola may reduce recovery time. "It may also enhance the ammonia re-assimilation and energy metabolism of the cell by increasing ATP, ribonucleic acid (RNA), protein and amino acid synthesis."
A 2007 clinical trial conducted in Austin, TX, found that a Swedish Rhodiola rosea extract demonstrated effective anti-depressive activity among patients with mild to moderate depression. This was a six week trial conducted on 89 subjects, ages 18 to 70. By the end of the study, the Rhodiola group experienced significant reductions in insomnia, emotional instability and somatization (the generation of physical symptoms from a psychiatric condition, such as anxiety). Furthermore, no adverse effects were detected.
Focus booster debate
Although rosea is anecdotally claimed to improve focus and attention, scientific studies suggest a less significant reality. It can improve fatigue and mental energy. In addition, human ADHD studies show Rhodiola can improve feelings of sluggishness. But don't expect anything dramatic. If you are looking to increase attention, examine our nootropics category. 
The proper dose depends highly upon the type of extract and the benefits you wish to accrue. The most available Rhodiola rosea extracts are standardized to a minimum of 3% rosavins and 1% salidrosides, as the naturally occurring ratio of the aforementioned compounds is around 3:1. A quality rosea product should provide this information on the label. Human clinical studies suggest that 150 to 600mg two to three times daily is a proper dose. It is important to remember to avoid rosea before sleep or in the late evening. You may experience mild symptoms of insomnia.
These statements are not approved by the FDA, are not intended to prevent or cure any illness, does not constitute medical advice and you should always consult your doctor before trying this supplement.
Rosavins and salidrosides
These are the standard by which companies test for genus purity, and were formerly thought to be the active constituents of Rhodiola rosea extracts. Recent evidence suggests that many other chemicals contribute to its effects, however, which is why stronger extracts aren't common.
Rosavins is the collective term for the phenylpropanoids in rosea (rosavin, rosarin and rosin).
Salidroside, also called rhodiolside, is a phenylethanol derivative -- along with tyrosol, an antioxidant also found in Rhodiola, that is critical for therapeutic activity.
This dynamic herb stacks with just about anything other than hardcore stimulants, due to its activity as a MAO Inhibitor. We urge against using it with PEA or anything stronger than caffeine. See side effects below.
We are most interested in a pure product that has 3% rosavins and 1% salidrosides, and no proprietary formula. However, there are some other products worth noting:
NUTRILITE(R) Rhodiola 110 vs. others
Rhodiola 110 is nothing more than a Rhodiola extract with caffeine, low levels of vitamin C, spinach and acerola cherry extract.
Although caffeine may synergize with Rhodiola rosea, the ridiculous price, in comparison to other extracts, does not justify its use. Additionally, you only receive 100mg of Rhodiola, which is on the lower end of the recommended dose from clinical human studies. And they do not specify if their product contains the proper 3:1 rosavin to salidroside ratio.
Therefore, we suggest you purchase a less expensive product with a more transparent ingredient list, such as those listed here.
Pill vs. powder
After sampling both, I recommend pill formulations if you cannot tolerate pungent flavors.
The rosea powder has a very bitter flavor that lingers on the palate. The benefits of purchasing powder are that it's generally cheaper and easier to control dosing.
When comparing various brands, the most important detail is whether the product mentions the proper rosavin/salidroside ratio. This is the pharmaceutical standard in Russia, and you may not receive all the benefits of Rhodiola rosea otherwise.
Very few side effects have been reported.
For those prone to anxiety, Rhodiola rosea may exacerbate problems, causing nervousness or agitation.
This response suggests that a smaller dose should be used.
Certain components of Rhodiola inhibit monoamine oxidase (MAOIs), and should not be taken with stimulants or PEA-based compounds, unless specifically instructed by a doctor.
Because of R. rosea's stimulatory effect, avoid taking it before sleep.
Combining with stimulants
Rosea has MAOI (MAO Inhibition) properties, and every stimulant label (psudeoepehedrine included) warns of a possible hypertensive crisis if combined with MAOIs. However, Rhodiola is a reversible inhibitor, possibly reducing the danger.
Labels typically state that you should not take OTC congestion medications if you have taken a MAOI within the past few weeks. Only irreversible inhibitors have such lengthy coverage.
R. rosea is proven to have a very low level of toxicity. In rat studies, the LD50 (lethal dose at which 50% of animals die) is approximately 3360 mg/kg. The human equivalent would be about 235,000 mg, rendering a huge margin of safety.
Thus, if the average daily dose is 600mg, the average person would have to consume around 392 daily doses to approach lethal concerns. 
As always, before you begin any diet or supplement program, consult with your doctor and get his or her written consent. No statements on this page have been approved by the FDA, and we are not doctors, so consult yours -- especially if using any prescription drugs. Rhodiola is never intended to cure, treat or diagnose any disease.
Where to buy
You typically won't find a good of a selection at your local health food store. It's always cheaper to buy online, where you'll also have more options.
Here on PricePlow.com, we compare prices on all supplements across several stores, getting you the best deal for your money. See the price comparisons on this page to save the most on Rhodiola rosea.
The best Rhodiola supplement
Again, we're looking for 3% rosavins and 1% salidrosides -- and one of our favorite value brands, NOW Foods, hits this on the nose.
NOW is a trusted supplement company that formulates their products in cGMP-certified labs and keeps the marketing budget low -- yielding a high-value product. Just what we look for.
So what is an adaptogen? The origin of the term can be traced back to a Russian scientist named Lazarev, who coined the term adaptogen in 1947. This is an agent -- a specific or group of chemicals, plant-based or otherwise -- that helps an organism neutralize hostile physical, chemical or biological stressors by engendering a nonspecific resistance.
Adaptogens, such as Rhodiola, have been shown to "increase the availability of energy during the day, reduce stressed feelings, increase endurance, and increase mental alertness." Thus, Rhodiola rosea is a beneficial addition to anyone's health stack.
Many claims, both fantastical and diverse, have been made about this plant. Equally substantial is its history for human use, having been mentioned in Greek medical texts, as well its use among 21st century Russian astronauts.
It's also known as golden root, rose root, roseroot, Aaron's rod, arctic root, king's crown, Lignum rhodium and orpin rose.
In places such as Sweden and Russia, a standardized extract is prescribed for the treatment of depression, fatigue, dementia and other conditions.
Nicotinic acetylcholine activation
Rhodiola actually specifically activates the nicotinic acetylcholine receptor group. There are two known acetylcholine receptor groups whose names derive from the respective chemicals that activate them: nicotinic and muscarinic, triggered by nicotine and muscarine respectively.
These are both implicated in cognition and memory formation. Nicotinic receptors are ionotropic (allow ions such as Na and K to enter the cell) and muscarinic receptors are metabotropic (cascading signal transduction via ions coupled with G-proteins -- a much more convoluted process).
The important detail is that nicotinic receptor activation is short term, whereas muscarinic activation produces more lasting effects on the neuron.
Shevtsov VA, et al; Phytomedicine; "A randomized trial of two different doses of Rhodiola rosea extract versus placebo and control of capacity for mental work;" 2003
American Botanical Council; "Swedish Rhodiola rosea Extract Effective in Treating Mild to Moderate Depression in New Clinical Trial;" 2007
Khanum F., et. al.; Comprehensive Reviews in Food Science and Food Safety; "Rhodiola rosea: A versatile Adaptogen;" 2005
Panossian A., et. al.; Phytomedicine; "Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy;" 2010
Rhodiola Rosea News on PricePlow
May 18, 2018 Blog Post:
Beast Super Test: Man’s Best Friend in Eight Capsules Per Day
The new version of Beast Super Test is one crazy interesting natural testosterone supporting supplement, with some well-researched ingredients and...
May 08, 2018 Blog Post:
Dedicated Nutrition BCAA Sensation: The Right Way to BCAA
Dedicated Nutrition BCAA Sensation is exactly what we like to see out of a BCAA! A 7.5g 4:1:1 ratio, added rhodiola, taurine, grape seed, and more!
Apr 20, 2018 Blog Post:
Dedicated Nutrition Brings an UNSTOPPABLE Gym Experience
Dedicated Nutrition's legendary pre workout supplement, UNSTOPPABLE, invades the shores of the US. With lower caffeine, can the rest make up for it?
Jan 29, 2018 Blog Post:
Zhou Neuro-Peak: Amazon’s $20 Nootropic for Beginners?
Zhou Nutrition Neuro Peak is one of the best-selling nootropics on Amazon, but is it all hype? We break it all down to see if it's worth it!
Jan 16, 2018 Blog Post:
CogniKeto: The Ketogenic Nootropic by Sparta Nutrition
CogniKeto is a new ketogenic nootropic brain boosting supplement from Sparta Nutrition to help brain function with BHB salts and powerful nootropics
Jan 15, 2018 Blog Post:
Performax Labs FitMax: Taking Weight Loss Drinks to the MAX!
Performax Labs relaunches a feel-good fat burning powder FitMax, touting a formula that combines a number of proven synergists for max effectiveness.
Jan 13, 2018 Blog Post:
Primeval Labs Neanderthal Ingredients: Explained by PricePlow
Looking for a strong test booster? CJ of PricePlow fame gives you the low down on all the label for the robust Primeval Labs Neanderthal ingredients.
Dec 04, 2017 Blog Post:
Optimum Nutrition Pro Pre: A Bigtime Pre Workout from a Big Brand
Optimum Nutrition Pro Pre finally brings a real pre workout to ON with the clinically-dosed Pro Pre - and there's three feel-good ingredients inside.
Nov 30, 2017 Blog Post:
Jacked Factory PumpSurge: Pumps & Focus from the ALTIUS Crew
Want pumps and focus while training without the stims? Try the nootropic nitric oxide fueled stim-free pre workout from Jacked Factory -- PumpSurge.
Oct 17, 2017 Blog Post:
Primeval Labs Neanderthal — Unleash your Inner Man Beast
Primeval Labs looks to revolution the natural testosterone booster market with Neanderthal, a powered natural testosterone booster with 11 ingredients
Sep 08, 2017 Blog Post:
Genius Joy Supplement Brings Heightened Cognition AND Mood
Genius JOY is a combination of nootropic and mood enhancing ingredients designed to alleviate stress and beat the blues. Have you used SAMe yet??
Jul 28, 2017 Blog Post:
The Socialite by NooWave: A Supplement Remedy for Introverts
The Socialite by NooWave is a revolutionary cutting edge anxiolytic mix of ingredients to increase an introvert’s energy and reduce social anxiety.
Mar 28, 2017 Blog Post:
Black Lion Research NOOTROL – Your Next Gen Nootropic
Black Lion Research Nootrol is a next-generation nootropic that looks to enhance brain function, IQ, focus, and mood - with some very new ingredients!
Mar 08, 2017 Blog Post:
Genius PRE Workout: Train Smarter AND Harder
Genius Pre is a clinically dosed, stimulant free pre workout that enhances focus but won't leave you feeling bottomed out from a rush of caffeine.
Feb 23, 2017 Blog Post:
Ghost Legend – A Pre Workout Fit for Legends
Ghost has reformulated their headlining pre workout Ghost LEGEND -- it's now 100% transparent and significantly more powerful.
Feb 07, 2017 Blog Post:
Blackstone Labs Hype Extreme: Long-Lasting Pumps & Focus
Hype Extreme is a brand new stimulant free pre workout from Blackstone labs that significantly enhances pumps and focus.
Jan 20, 2017 Blog Post:
ATP Nutrition Perform Kinetics: The Perfect Surprise Pre Workout
ATP Nutrition has crafted the ultimate performance enhancing pre workout in Perform Kinetics, and we LOVE it! Why? High-dose TeaCrine!
Jan 04, 2017 Blog Post:
HAKNutrition PreHAK – The Ultimate Workout Hack!
HAKNutrition is a new supplement company with PreHAK, an incredibly well dosed pre workout supplement that makes the perfect "hack" for your workout!
Dec 07, 2016 Blog Post:
PES Prolific – PEScience is Back in the Pre Workout game!
PES Prolific brings PEScience back into the stimulant pre workout market - it's a performance and focus centric pre workout for the intelligent lifter
Nov 13, 2016 Blog Post:
Best Gaming Supplement Buyer’s Guide: 2018’s Top 10
What's the best gaming supplement... for YOU?! PricePlow's latest guide steps you through shopping for gaming supplements. Look out for that MOD!
Oct 07, 2016 Blog Post:
Blue Star Elevate: Maximum Mental Muscle Potential!
Blue Star Elevate is an incredibly well crafted nootropic-based supplement that enhanced focus, mood, cognition, and drive.
Sep 26, 2016 Blog Post:
Olympus Labs BloodShr3d: Finally a REAL Fat Burning Drink!
BloodShr3d from Olympus Labs is the brands answer to those looking for a powerful, and delicious, thermogenic weight loss aid. Get ready for energy!
Aug 25, 2016 Blog Post:
MOD Gaming Supplement – Amp up your Gaming Focus!
The MOD Gaming Supplement is a very well-dosed, focus-based supplement for eSports gamers that provides some energy, but more smooth, controlled focus
Aug 08, 2016 Blog Post:
RedCon1 Big Noise: Focused Bunker Busting Pump-Bombs!
RedCon1 Big Noise is a stimulant-free pre workout supplement that will keep you FOCUSED even without the stimulants: The highest level of readiness!
Jul 27, 2016 Blog Post:
SuperPump 250 is BACK from Gaspari!
The one time king of pre workouts is BACK! Gaspari Nutrition has reformulated their outstanding pre workout SuperPump 250!
Jul 22, 2016 Blog Post:
First Finisher Champion Performance Powder: Gains for Miles
First Finisher is a new supplement company whose mission is to create CHAMPIONS. Their stim-free pre workout Champion Performance Powder will do just that!
Apr 25, 2016 Blog Post:
Optimum Nutrition Gold Standard BCAA
Optimum Nutrition has further expanded its Gold Standard line of products with the additon of a BCAA product aimed to help boost recovery and immunity.
Dec 29, 2015 Blog Post:
Olympus Labs TR1UMPH: Next-Gen Muscle Builder
Olympus Labs TR1UMPH is an all new formulation muscle-builder that's retooled to be all natural for gains and recovery, based on phosphatidic acid!
Nov 23, 2015 Blog Post:
Rich Piana’s MENTALITY – Cognitive Booster Leaves *Nothing* Out
Rich Piana's Mentality is a cognition boosting supplement that contains virtually every nootropic and amino acid to elevate memory and mental function.
Nov 02, 2015 Blog Post:
Olympus Labs Conqu3r Unleashed Stim-Free: Loaded to the Gills!
Conqu3r Unleashed Stim-Free is the Olympus Labs caffeine-free pre workout unveiled with 5 patented ingredients all clinically dosed.
Oct 01, 2015 Blog Post:
Carbon PREP – Layne Norton’s Pre Workout DOA
Carbon Prep is Layne Norton's debut nearly-stim-free pre workout for his brand new supplement line, Carbon. Let's see what's in store (it's LOADED!)
Jun 24, 2015 Blog Post:
Jack3d 2015 Updates Released
Jack3d has been updated for 2015 by USPLabs, revamping a majority of their ingredients and providing a smoother stimulant experience!
Apr 28, 2015 Blog Post:
PES Shift – The Ultimate Stackable Caffeine-Free Fat Burner!
PES Shift is set to release their newly reformulated caffeine free fat burner. Shift your weight loss stack towards effectiveness and stack it up!
Apr 13, 2015 Blog Post:
PreGains HodgeTwins Pre-Workout – Twin sized GAINZ!
Feb 18, 2015 Blog Post:
Rich Piana 5% KILL IT Pre Workout – Does it Kill?
Rich Piana's KILL IT Pre Workout Supplement from 5% Nutrition looks to have some decent energy and pumps, but there's some confusion to figure out..
Sign up for future Rhodiola Rosea news!
Click the button below to sign up for future Rhodiola Rosea news, deals, coupons, and reviews!
Rhodiola Rosea Deals & Price Alerts
The following deals are still active:
- May 18, 2018: NOW Rhodiola 60 Vcaps dropped by 7.5% to $8.09 at DPS Nutrition
- May 09, 2018: Enzymatic Therapy Rhodiola Energy 40 Capsules dropped by 22.2% to $7.69 at AllStarHealth
- Apr 11, 2018: Nature's Way Rhodiola Rosea 60 Vcaps dropped by 15.4% to $7.99 at AllStarHealth
- Jan 03, 2017: Jarrow Formulas Rhodiola Rosea 500 60 Capsules dropped by 8.7% to $13.50 at A1 Supplements
Sign up for future Rhodiola Rosea deals and coupons!
Click the button below to sign up for future Rhodiola Rosea deals, news, and coupons!