The brain is an exceptionally complex and delicate system. As many of you know there are endless supplements are dozens of compounds reported to be “nootropic” or to increase memory and learning. Many of these supplements simply increase acetylcholine (ACH). Unfortunately increasing ACH is a poor way to increase brain power when it is solely employed. In fact your more likely to have unfavorable side effects and reduced brain function, over time, when using racetams, Noopept etc without the proper ancillaries. Increased ACH is indicated in multiple brain disease states including Parkinsons. Taking a product that only increases ACH and doesnt balance out the other neurotransmitters involved can be hazardous. A testament to this is the widespread comments online regarding negative effects of Nootropic products.
“libido-killing/depression-inducing side effects have been one of the greatest obstacles standing in the way of trying to use any of the racetams consistently (not to mention the emotional dulling)”
“The imbalance between cholinergic activity and dopaminergic activity in the striatum causes a variety of neurological disorders, such as Parkinson’s disease.” https://www.ncbi.nlm.nih.gov/pubmed/20590830
“many people mention depression symptoms when using racetams, noopept and other things that increase ACH specifically.”
Initially with increased ACH there may be an increase in Dopamine and Serotonin but this quickly leads to depletion and side effects related to low dopamine and serotonin levels. NOOTROL, unlike most nootropic products, addresses these deficiencies with additional ingredients included specifically to balance out the high ACH levels. Every action has a reaction and in the brain its no different. Cognitive function involves the participation of many different neurotransmitter systems in a variety of brain areas. The centerpiece of investigation regarding cognitive function has classically been the cholinergic system, but it has become increasingly clear that other transmitter systems interact with cholinergic systems to provide the neural basis for cognitive function. In order for a nootropic product to work well the formula must be well balanced and each effects side effects must be addressed. Many/most nootropic products are either a single ingredient or a mix and match of random “nootropic” ingredients with little rhyme or reason. Black Lion Research Nootrol has been balanced perfectly. Now, everyone can improve their lives by harnessing the power of higher intellect.
Black Lion Research Nootrol works in multiple ways to increase cognitive function and brain health. Increased acetylcholine is a part but so is increased cerebral circulation, antioxidant activity and optimizing of neurotransmitters involved in memory, learning and brain power. Black Lion Research Nootrol also increases neurotrophic factors such as BDNF and NGF.
BDNF- Brain derived neurotrophic factor Brain-derived neurotrophic factor (BDNF) is a key protein in brain plasticity and is particularly important for survival of dopaminergic neurons. BDNF is involved in new neural network formation, neuroplasticity, Long term memory formation, helps to support the survival of existing neurons and encourages the growth, regeneration and creation of new neurons and synapses. BDNF increases energy metabolism in obese diabetic animals, partly through activating the stress response and inducing UCP1 – an uncoupling protein that creates brown fat, which is easily burned for fuel. BDNF can help with sleep, is antidepressant and can decrease insulin resistance. Unfortunately BDNF decreases with age. Increases in this neurotrophic factor are beneficial to health and cognitive function.
NGF- Nerve growth Factor Nerve growth factor (NGF) is one of a group of small protein like molecules called neurotrophins (BDNF is another) that are responsible for the development of new neurons, and for the health and maintenance of mature ones. NGF promotes growth, maintenance, and survival of neurons and axons (part where electrical signal passes). It also helps repair myelin sheath, the coating around the axons (R). Animal testing has shown that as production of NGF decreases in the brain, one’s ability to form new connections and to retain and access memories is impaired. NGF can save degenerating nerves and restore function. On top of NGFs effects regarding nerve regeneration and neural protection it can help increase serotonin and reduce depressive symptoms. Recent animal studies show that NGF selectively protects acetylcholine activated neurons.
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