Thorne Research Pyridoxal 5''-Phosphate - 180 Vegetarian Capsules Pyridoxine, also known as vitamin B6, is necessary for the transformation and utilization of amino acids for many functions in the body, including energy production and neurotransmitter synthesis. Vitamin B6 is also involved in the production of hemoglobin, intrinsic factor, and is a vital component in the formation of the myelin sheath that surrounds nerve cells. But in order for pyridoxine to be used by the body it must first be converted to pyridoxal 5''-phosphate (P5P), a process that takes place in the liver. Individuals with compromised liver function have difficulty making this conversion and consequently may be at risk of a vitamin B6 deficiency* Supplementing with Thorne''s Pyridoxal 5''-Phosphate ensures you receive the most bioactive form of vitamin B6. the active form of vitamin B6 more readily used by the body Pyridoxal 5''-Phosphate is yeast free without preservatives, magnesium stearate, or other lubricants and diluents made without flowing agents that can inhibit bioavailability Dr. Michael Lebowitz D.C. Recommends: This will often test to negate food sensitivities, prostaglandin imbalances, fluid retention, recurrent musculoskeletal problems, weak gluteal muscles, retrograde patterns, CCW and/or CW torques, and weakness of the pineal NL (GV-20). It will often strengthen weak neck and low back muscles. A majority of women on oral contraception or estrogen replacement therapy will show a need, as will patients on prednisone. PMS, carpal tunnel syndrome, and electromagnetic field sensitivity can all benefit from supplementing with P-5-P. This is the isolated vitamin Dr. Michael Lebowitz uses the most in his practice.