Thorne Research 5-MTHF 1 mg. - 60 Vegetarian Capsules
5-MTHF FolateAlso known as L-5-methyltetrahydrofolate or methylfolate, 5-MTHF is an active form of the essential B-vitamin folate that your tissues can utilize and absorb easily without delay. Some people have trouble converting folic acid into a form of folate the body can use because of intestinal issues, liver dysfunction, or genetics. This Thorne Research 5-MTHF professional supplement solves that problem for those who need help by delivering the active folate your body needs in sufficient levels. These methylfolate capsules are highly-absorbable, gluten-free, and perfect for foundational health and wellness, mood support, a healthy heart, and robust blood vessels.
What is 5-MTHF?
5-MTHF is a highly-absorbable form of folate, an essential B-vitamin also known as vitamin B9. It plays many important roles in the body from cell growth and DNA formation to energy levels and more. Who needs to use 5-MTHF? Professional supplements in general are best for people who have been recommended to use them by a healthcare practitioner, naturopath, or doctor. Women of childbearing age need an adequate amount of folic acid, not just women who plan to become pregnant. This is because half of pregnancies are unplanned and folic acid intake is vital before conception and during pregnancy. You might also need 5-MTHF Folate if your blood levels of vitamin B9 are low.
The main benefit of a daily 5-MTHF supplement capsule is to help maintain adequate levels of folate (vitamin B9) in the body’s system. The symptoms of insufficient folate or folic acid intake may include fatigue, headaches, difficulty concentrating, megaloblastic anemia, irritability, shortness of breath, changes in color of skin, hair, or nails, plus sores in or around the mouth. It has been found that people with low folate levels may be more prone to depression and other mood disorders. Plus, inadequate folic acid intake can contribute to birth defects. Maintaining proper levels of this important B-vitamin can help reduce the risk for these unpleasant, unwanted symptoms and help promote overall health and well-being.
Is 5-MTHF the Same as Folic Acid?
While 5-MTHF and folic acid are similar in many ways, they are not actually the same thing. Folic acid is a synthetic version of vitamin B9. It is a water soluble vitamin, which means the body uses it quickly and cannot store it – as long as the body is able to convert it into its useful and absorbable form of dietary folate called L-methylfolate. Its structure is very close to folate, the naturally occurring form of the essential vitamin B9 which is found readily in dark leafy greens and other food sources. Most people consider folic acid and folate to be the same thing and use the terms interchangeably. 5-MTHF skips the need for enzymatic conversion because it is already an active form of folate.
5-MTHF and Depression
Thorne Research’s 5-MTHF Methylfolate is often recommended by doctors and other healthcare practitioners to their patients who suffer from depression, anxiety, and other mood ailments. Research has shown that 5-MTHF Methylfolate B-vitamin may be effective for treating depression, especially for those who do not find antidepressants to work. Folate plays an essential role in the brain. Neurotransmitters such as dopamine and serotonin reply on folate for their formation. In individuals with low levels of folate or those who have difficulty converting folic acid into active folate, depression may be more prevalent. Supplementing your diet with Thorne Research’s 5-MTHF Methylfolate is a generally safe way to improve mood and get those neurotransmitters firing like they should.
Where to Buy Thorne Research Products
LuckyVitamin is a proud supplier of high-quality Thorne Research products. These professional supplements are manufactured according to strict quality standards. Thorne sources the most exceptional ingredients, they think sustainably, the manufacture the right way every time, and they test, test, then test again. They work alongside medical professionals, researchers, and engineers to develop science-based products and processes. Thorne has been trusted for over 30 years by healthcare practitioners, U.S. National Teams, and families like yours. Thorne Research’s values align with LuckyVitamin which has been your trusted health product seller online since 2004.
Folic acid must be converted to its active forms to be used by the body. This is a multi-step biochemical process that occurs in the intestines and liver. In the presence of intestinal or liver dysfunction this conversion may not occur sufficiently enough to meet the body's needs. Furthermore, up to 60-percent of the U.S. population may have a genetic enzyme defect that makes it difficult for them to convert folic acid into active 5-MTHF. For these individuals and many others, 5-MTHF supplementation may be a more effective method of folate repletion.
Because deficiencies of folic acid have been linked to low-birth-weight infants and neural tube defects, folic acid requirements double during pregnancy. The Centers for Disease Control and Prevention recommends folic acid supplementation for all women of childbearing age because the biggest need is during the first trimester, when a woman may not even be aware she is pregnant. Supplementation with the more active form may be preferable.
In concert with vitamin B12, 5-MTHF functions as a methyl-group donor involved in the conversion of the amino acid homocysteine to methionine. Methyl-group donation is vital to many biochemical conversion processes, including the synthesis of serotonin, melatonin, and DNA.
It is important for women of childbearing age to get enough folic acid - not just those who are planning to become pregnant. Only 50 percent of pregnancies are planned, so any woman who could become pregnant should get enough folic acid every day - especially before conception and during early pregnancy.
- a breakthrough in folate supplementation
- the most bioavailable, active form of folate
- an excellent source of folate for pregnant women
- supports optimal cardiovascular and neurological function
- made without flowing agents that can inhibit bioavailability
Dr. Michael Lebowitz D.C. Recommends:
Many people have difficulty or an inability to convert inactive folic acid to its bioactive form. 5-MTHF is the most bioactive form. It acts as a methyl donor and is involved in neurotransmitter synthesis and nitric oxide production. From an AK standpoint, Dr. Michael Lebowitz D.C. tests this as well as Folacal and Folic Acid Liquid and lets his test results decide which supplement to prescribe.
Thorne Research's Mission
At Thorne Research, their mission is to enhance the health and well-being of people by providing superior dietary supplements that have the highest level of quality and purity – thereby creating the most respected and valued company in the dietary supplement industry.
The Thorne Difference.
For more than 25 years, Thorne has relentlessly pursued the highest possible quality and bioavailability in dietary supplements. At Thorne, they actually manufacture products that they sell – a key difference that allows Thorne to control every aspect of the manufacturing process and ensure that every Thorne product is in pure, completely hypoallergenic form, and without the common additives, flowing agents, and binders used throughout the industry.
A few other companies have tried to do what Thorne does, and many others claim to have the same philosophy and quality, but nobody has been able to duplicate what Thorne's clients call "Thorne Quality." Thorne has changed the industry in many ways over the past two decades, and they continue to raise the bar and set new standards in product formulation, raw material purity, manufacturing, and quality control.
Thorne's Commitment to Purity
Practitioners have become accustomed to seeing the vague "We use only the purest ingredients" in the promotional materials of almost every dietary supplement company. Perhaps these companies truly believe that. Perhaps they don't know any better. Nevertheless, Thorne Research, for more than 25 years, has been the standard by which companies in the industry are judged for product purity. Practitioners rely on Thorne as the company they trust for their extremely allergic, chemically sensitive, and immune-compromised patients.
Purity Takes Extra Effort
For example, instead of purchasing prediluted vitamin D, as other companies do, Thorne performs its own dilution to avoid detrimental ingredients, such as the preservatives or lactose that are found in many commercially available dilutions. Why must vitamin D be diluted? Because in its pure form, it is too concentrated to safely blend into a vitamin product. Pure vitamin D is 40 MILLION International Units (IU) per gram. The RDA for adults is 600-800 IU per day. To ensure proper mixing, it must be made into a dilute powder that flows and does not lose potency. So, unlike companies that use prediluted vitamin D that contains unacceptable excipients and preservatives, at Thorne, pure pharmaceutical vitamin D is first blended with pure mixed tocopherol vitamin E, and the resultant stable vitamin D is then blended with hypoallergenic cellulose powder. The final powder is blended in a large tumble blender and subsequently analyzed. Not only is the final product stable; it is also hypoallergenic and can be mixed homogeneously and at a safe level with other powders. Just as with vitamin D, Thorne utilizes similar processes for other raw materials, such as vitamin K, leaving it to other companies to purchase commercially available raw materials filled with unacceptable ingredients and preservatives.
Ingredients You Don't Want
Magnesium Stearate: Good for speed-hungry encapsulating machines. Not necessarily good for you. Manufacturing encapsulated dietary supplements isn't easy. Pure powdered ingredients are difficult to mix because they are either extremely dry, sticky with botanical oils, or attract unwanted moisture. So most manufacturers add magnesium stearate and other agents such as lactose and dextrose to make the powder flow quickly and easily through their high-volume machines. Problem is, these additives may compromise the bioavailability of the nutrients in the supplement, and might cause allergenic problems. At Thorne, they take a different approach.
Thorne will never utilize large fatty acid excipients in its manufacturing processes – ingredients such as magnesium stearate or stearic acid. These excipients are utilized as flowing agents to ensure that maximum productivity is obtained from capsuling and tableting machines. There are documented detrimental effects directly attributed to long chain fatty acids utilized as manufacturing flowing agents. Every qualified pharmaceutical compounder recognizes that large fatty acids, such as magnesium stearate, can interfere with product dissolution and influence absorption. Virtually all companies, because of the economic impact, ignore this data. As with most industries, the bottom line dictates the level of quality. The dietary supplement industry has one exception: Thorne Research, the company that does not compromise. Nevertheless, if a company cannot manufacture products without using detrimental excipients, they should not allude to being either "hypoallergenic" or "pure."
The Bottom Line?
Thorne is the only hypoallergenic dietary supplement manufacturer with the highest degree of purity that you – and your most severely allergic, chemically sensitive, and immune-compromised patients – can truly trust.
Quality Ingredients: A Higher Standard
At Thorne, they are committed to setting a higher standard of quality when it comes to ingredients. To produce their truly hypoallergenic encapsulated supplements, Thorne uses only the purest and finest ingredients available.
Every manufacturer has two basic options when purchasing raw materials: purchase either truly pure raw materials, or purchase raw materials to which substances have been added to facilitate manufacturing. This fundamental dilemma translates to these very typical questions: "Do I purchase pure vitamin C or vitamin C with additives?" "Do I purchase pure B vitamins or coated B vitamins for taste masking?" "Do I purchase pure enzymes such as pancreatin, pepsin, and bromelain or enzymes diluted with lactose?"
There are few commercial sources for vitamins B12, D, K, or biotin that are not diluted with substances such as lactose, cornstarch, and preservatives such as BHT. That's why Thorne developed methods that allow them to use pure, undiluted sources of these nutrients – and many others. It's just one more example that when it comes to quality, what everyone else accepts as an industry standard isn't good enough. While some companies say they are raising their standards....at Thorne they set them.