Nootropics Depot CyaTherm - Thermogenic Enhancer

About Cyatherm Capsules

Cyatherm Capsules deliver a comprehensive thermogenic formula that combines seven research-backed botanicals to support your body's natural energy processes. Each ingredient targets a different aspect of thermogenesis, from CaloriBurn's brown adipose tissue support to Black Rice Extract's cyanidin-3-glucoside for metabolic support. This multi-pathway approach helps support healthy metabolism and energy expenditure through natural thermogenic processes.

Our Cyatherm Story

Most thermogenic supplements on the market rely heavily on stimulants or single-ingredient approaches that only address one piece of the metabolic puzzle. We saw an opportunity to create something more comprehensive by targeting multiple thermogenic pathways simultaneously. Rather than just cranking up your nervous system, we wanted to support the natural mechanisms your body uses to generate energy.

We combined novel ingredients like CaloriBurn grains of paradise extract for brown adipose tissue support with traditional botanicals like Black Ginger Extract and unique compounds like Ecklonia cava marine algae. We added precise doses of supporting ingredients including chromium for metabolic function and piperine to enhance absorption of the entire formula. The result is a comprehensive thermogenic formula supporting healthy metabolism through multiple complementary pathways rather than relying on stimulants alone.

Benefits

• Supports Thermogenesis: Cyatherm enhances your body's natural heat production through multiple pathways, featuring CaloriBurn to promote brown adipose tissue activity and Ecklonia cava to support thermogenic processes.
• Supports Healthy Metabolism: The formula supports healthy glucose metabolism and insulin function with Black Rice Extract and Chromium, helping your body efficiently utilize macronutrients for sustained energy production.
• Enhanced Workout Energy: Black Ginger Extract supports mitochondrial function to promote physical endurance and recovery, making it ideal for active lifestyles and regular exercise routines.
• Provides Antioxidant Support: The combination includes anthocyanins from Black Rice Extract for antioxidant support, while Ecklonia cava's unique properties help create a balanced, well-tolerated formula.

Piperine enhances bioavailability while acting as an additional thermogenic compound, ensuring maximum absorption and effectiveness of all active ingredients for comprehensive metabolic support.

Quality and Standardization

• Research-Grade Standardization: We standardize each ingredient to match contemporary research specifications, including 125 mg of cyanidin-3-glucoside in our Black Rice Extract and 12.5 mg of 6-paradol in CaloriBurn, ensuring consistent potency across every batch.
• Verified Sourcing Partners: We work directly with verified suppliers to secure premium ingredients like Black Ginger Extract and Ecklonia cava, standardized for their key active compounds including 5,7 dimethoxyflavone and dieckol.
• cGMP Certified Manufacturing: Our Tempe, Arizona production facility maintains current Good Manufacturing Practice certification, adhering to the highest industry protocols for safety, potency, and purity in every capsule.
• Comprehensive Third-Party Testing: Each ingredient undergoes identity verification and contaminant screening at ISO-accredited laboratories before encapsulation, with finished products receiving additional rounds of potency, purity, and stability testing.
• Complete Transparency: Every bottle delivers traceable science and validated testing results, backed by our commitment to responsible supplement production and complete ingredient transparency.

Mechanism of Action

• Brown Adipose Tissue Support: CaloriBurn's 6-paradol supports brown adipose tissue in its natural role of converting calories to heat through thermogenesis, while Ecklonia cava provides additional thermogenic support alongside properties that help create a smooth overall experience.
• Mitochondrial Enhancement: Black Ginger's polymethoxyflavones promote mitochondrial efficiency, supporting the cellular powerhouses responsible for energy production and supporting physical performance and endurance capacity.
• Adrenergic Response Support: Rauwolscine supports healthy adrenergic response, which serves as one of the primary biological pathways for supporting thermogenesis and metabolic function throughout the body.
• Glucose Metabolism Support: Black Rice Extract's anthocyanins, particularly cyanidin-3-glucoside, help maintain healthy carbohydrate metabolism while chromium supports healthy insulin signaling pathways.
• Enhanced Bioavailability: Piperine enhances the absorption of all other ingredients while also contributing its own thermogenic properties, maximizing the supplement's overall effectiveness and metabolic support.

Overview of the Science

Cyatherm's formulation is grounded in documented scientific literature and reflects a commitment to evidence-based supplement development. Clinical studies on Aframomum melegueta (the source of CaloriBurn) have demonstrated increases in energy expenditure and modest, statistically significant impacts on body composition markers, supporting its role in thermogenic support ^[1][2]. Research suggests Cyanidin-3-glucoside from Black Rice Extract supports healthy oxidative balance and metabolic parameters such as glucose and lipid function ^[3][4][5]. Studies indicate Kaempferia parviflora (Black Ginger) supports mitochondrial biogenesis and exercise capacity, with encouraging results in both preclinical and clinical models ^[6][7].

Research suggests Ecklonia cava's polyphenols support healthy metabolic function and balanced oxidation levels ^[8]. Chromium is a widely used dietary mineral with established evidence supporting its role in helping maintain healthy blood sugar metabolism ^[9][10]. Rauwolscine is included based on its adrenergic effects ^[11]. Altogether, Cyatherm's multi-ingredient design is based on a combination of robust science and emerging research, supporting the physiological foundations of energy, metabolism, and wellness while adhering to regulatory boundaries for dietary supplements.

^[1] Sudeep HV et al. Drug Des Devel Ther. 2022;16:3777-3791.

^[2] Sugita J et al. J Nutr Sci Vitaminol. 2014;60:22-27.

^[3] Um MY et al. J Sci Food Agric. 2013;93(15):3126-33.

^[4] Zheng H et al. J Agric Food Chem. 2020;68(15):4399-4410.

^[5] Kim MB et al. [...]. 2018;14(7 Suppl):P293-P295.

^[6] Kim MB et al. J Med Food. 2018;21(1):30-38.

^[7] Matsushita M et al. J Nutr Sci Vitaminol. 2015;61(1):79-83.

^[8] Lee HJ et al. J Functional Foods. 2018;46:356-364.

^[9] Balk EM et al. [...] Care. 2007;30(8):2154-2163.

^[10] Bahijiri SM et al. Saudi Med J. 2000;21(9):831-7.

^[11] Arthur JR et al. Br J Pharmacol. 1984;83(3):717-28.

Ingredients

• Essential trace mineral that supports healthy glucose metabolism and insulin sensitivity
• Ingredient source: Chromium from 20 mg Crominex 3+ stabilized with Capros amla extract (fruit) and PrimaVie shilajit
• Amount per serving: 400 mcg
• Primary benefit: Supports healthy blood sugar levels already within the normal range

• Anthocyanin-rich extract that supports healthy metabolic function and oxidative balance
• Ingredient source: Black rice extract (Oryza sativa) seed
• Amount per serving: 500 mg
• Standardization: 125 mg cyanidin 3-glucoside
• Primary benefit: Provides antioxidant support and promotes healthy glucose metabolism

• Marine brown algae extract that supports healthy metabolic processes and cellular function
• Ingredient source: Ecklonia cava (whole alga)
• Amount per serving: 250 mg
• Standardization: 1.25 mg dieckol
• Primary benefit: Supports healthy inflammatory response and metabolic function

• Standardized Aframomum melegueta extract that supports healthy thermogenic processes
• Ingredient source: CaloriBurn (Aframomum melegueta) seed extract
• Amount per serving: 100 mg
• Standardization: 12.5 mg 6-paradol
• Primary benefit: Supports healthy energy expenditure and metabolic function

• Kaempferia parviflora extract that supports healthy circulation and energy metabolism
• Ingredient source: Black ginger extract (Kaempferia parviflora) root
• Amount per serving: 50 mg
• Standardization: 5 mg 5,7-dimethoxyflavone
• Primary benefit: Supports healthy blood flow and metabolic efficiency

• Black pepper alkaloid that supports absorption and bioavailability of formula actives
• Ingredient source: Piperine extract (Piper nigrum) seed
• Amount per serving: 6 mg
• Standardization: 95% piperine
• Primary benefit: Promotes enhanced absorption and more efficient ingredient utilization

• Alpha-2 adrenergic receptor antagonist that supports healthy metabolic processes
• Ingredient source: Rauwolscine (Rauwolfia vomitoria) root
• Amount per serving: 0.5 mg
• Standardization: 95% rauwolscine
• Primary benefit: Supports healthy fat metabolism and energy utilization

Lab Testing Results / Certificate of Analysis (COA)

• CTHCS1072225
• CTHCS2072225
• CTHCS2022326
• CTHCS1022326
• CTHCS1052626

Frequently asked questions

1. How long until Cyatherm starts working?

   Cyatherm delivers immediate effects for some users, with most people reaching full results within 2-3 days of consistent daily use.

2. What ingredients are in Nootropics Depot's Cyatherm?

   Cyatherm contains seven botanicals: CaloriBurn (Aframomum melegueta), Black Rice Extract, Ecklonia cava, Black Ginger Extract (Kaempferia parviflora), and Chromium, among others. Each ingredient targets a different aspect of thermogenesis and metabolic support.

3. What makes Nootropics Depot's Cyatherm different?

   Our Cyatherm formula targets thermogenesis through seven research-backed botanicals simultaneously, including CaloriBurn for brown adipose tissue support and Black Rice Extract for metabolic support, rather than relying on stimulants or a single-ingredient approach.

4. Does Cyatherm work without exercise?

   Cyatherm supports thermogenesis and healthy metabolism through its multi-ingredient formula regardless of activity level, though combining it with regular exercise will amplify those benefits.

5. Is Chromium Picolinate safe?

   Chromium Picolinate is generally recognized as safe at supplemental doses, and our Cyatherm formula includes it as part of a carefully balanced thermogenic blend. As with any supplement, consult your healthcare provider if you have existing health conditions or take medications.

6. What is Chromium Picolinate?

   Chromium Picolinate is a highly bioavailable form of the essential trace mineral chromium, paired with picolinic acid to enhance absorption. In Cyatherm, it supports healthy glucose metabolism and insulin function to help your body efficiently utilize macronutrients for energy.

7. When should you take Chromium Picolinate?

   Our Cyatherm Capsules, which include Chromium Picolinate as part of the formula, are best taken in the morning. Two capsules once daily, with or without food, is the recommended serving.

8. Does Chromium Picolinate help you lose weight?

   Chromium Picolinate supports healthy glucose metabolism and insulin function, helping your body efficiently utilize macronutrients rather than acting as a direct weight loss agent. It works best as part of a broader thermogenic formula like Cyatherm, which combines multiple ingredients targeting different metabolic pathways.