Zinc (from PepZinGI Zinc-L-Carnosine Complex) – 16 mg (150%)
A complex of elemental zinc bound to L-carnosine, designed to support gastrointestinal lining and zinc bioavailability.
- Supports stomach lining integrity and promotes gut healing.
- Enhances immune defense by regulating T-cell function.
- Aids in enzyme activity essential for digestion and DNA repair.
- Promotes intestinal mucosal repair and resistance to inflammation.
Synergy: Works with gut-support agents (like licorice and CoreBiome) to fortify gut wall integrity.
- Matsukura N, Tanaka N. Aliment Pharmacol Ther. 2000;14 Suppl 1:8–13.
- Prasad AS. Curr Opin Clin Nutr Metab Care. 2009;12(6):646–652.
- Wada T et al. J Pharmacol Sci. 2007;104(1):27–35.
Guar Gum Fiber Powder – 1,000 mg
A water-soluble dietary fiber derived from the guar bean (Cyamopsis tetragonolobus).
- Promotes bowel regularity and stool normalization.
- Serves as a prebiotic, supporting healthy gut flora.
- Slows gastric emptying to enhance nutrient absorption.
- May aid in regulating blood glucose levels post-meal.
Synergy: Enhances probiotic colonization by supplying fermentable substrate.
- Slavin JL. Adv Nutr. 2013;4(2):141–150.
- Jovanovski E et al. Am J Clin Nutr. 2019;109(2):471–487.
CoreBiome Tributyrin – 545 mg
A patented short-chain fatty acid (SCFA) source delivering butyrate, crucial for gut lining integrity and microbiome health.
- Fuels colonocytes and strengthens gut epithelial barrier.
- Modulates inflammation via histone deacetylase inhibition.
- Enhances gut motility and tight junction function.
- Supports microbial diversity and immune modulation.
Synergy: Butyrate’s benefits are enhanced by probiotics and prebiotics (e.g., guar gum and fiber blends).
- Canani RB et al. World J Gastroenterol. 2011;17(12):1519–1528.
- van der Beek CM et al. J Nutr Biochem. 2017;42:1–11.
Digexin (Ashwagandha Root & Okra Fruit Extracts) – 300 mg
A blend of adaptogenic Ashwagandha and antioxidant-rich okra, targeting stress and gut health.
- Reduces cortisol and enhances resilience to digestive stress.
- Ashwagandha supports GI barrier integrity and HPA axis balance.
- Okra provides mucilage and antioxidants that soothe mucosal irritation.
- Together, they support microbiome balance under stress.
Synergy: Complements zinc and butyrate for stress-induced gut disruption.
- Chandrasekhar K et al. Indian J Psychol Med. 2012;34(3):255–262.
- Lengsfeld C et al. Planta Med. 2004;70(1):62–67.
GutGard DGL Licorice Extract – 155 mg
A flavonoid-rich, deglycyrrhizinated form of licorice standardized to support digestive function without raising blood pressure.
- Soothes the gastrointestinal lining and promotes mucosal defense.
- Inhibits H. pylori and supports microbiome homeostasis.
- Reduces intestinal inflammation and acid-induced damage.
- Supports upper GI comfort and ulcer resistance.
Synergy: Works with zinc-carnosine and butyrate to protect gastric epithelium.
- van Marle J et al. J Ethnopharmacol. 2006;107(2):219–224.
- Mowrey DB. Lancet. 1986;328(8505):817–818.
DigeZyme Multi Enzyme Complex – 150 mg
A blend of digestive enzymes including amylase, protease, lipase, cellulase, and lactase.
- Enhances macronutrient breakdown and absorption.
- Reduces digestive discomfort and postprandial bloating.
- Supports nutrient assimilation in enzyme-deficient individuals.
- Promotes gut efficiency under high-stress, high-protein diets.
Synergy: Complements probiotics and fiber for overall digestive capacity.
- Martinsen TC et al. World J Gastroenterol. 2005;11(18):2832–2838.
- Borrelli F et al. Neurogastroenterol Motil. 2009;21(8):823–832.
Quadruple-Coated Probiotic Blend – 1 Billion CFU (Total)
A blend of 5 probiotic strains designed for enhanced survivability through the digestive tract.
- Supports gut microbiome diversity and colon health.
- Reinforces intestinal barrier and mucosal immunity.
- Helps manage GI upset, irregularity, and bloating.
- May improve nutrient absorption and vitamin synthesis.
Strain breakdown:
- L. rhamnosus GG (400M) – Supports immune regulation.
- L. plantarum 299v (200M) – Aids IBS symptom reduction.
- B. longum (150M) – Balances mood-gut axis and digestion.
- L. salivarius (150M) – Oral-gut crossover immunity.
- B. coagulans (100M) – Spore-forming resilience for survivability.
Synergy: Enhanced by prebiotic fiber and SCFA producers like CoreBiome.
- Ouwehand AC et al. Br J Nutr. 2002;87(S2):S153–S157.
- Marteau P et al. Gut. 2001;48(3):343–347.
AstraGin (Panax notoginseng + Astragalus membranaceus) – 50 mg
- What it is: A patented adaptogenic compound shown to enhance nutrient absorption and gut integrity.
- Boosts absorption of amino acids, vitamins, and fatty acids.
- Promotes gut lining regeneration and tight junction restoration.
- Modulates gut inflammation and supports microbiome balance.
- Increases bioavailability of co-formulated ingredients.
Synergy: Amplifies uptake of zinc, butyrate, fiber, and enzymes.
- Yang H et al. J Agric Food Chem. 2014;62(30):7082–7089.
- Hu Z et al. Phytother Res. 2014;28(2):187–194.
Synergy Overview
Barrier Defense: Zinc carnosine, licorice, butyrate, and ashwagandha strengthen epithelial walls.
Digestive Efficiency: DigeZyme enzymes and probiotics improve nutrient breakdown and utilization.
Microbiome Balance: Prebiotic fiber, CoreBiome butyrate, and probiotics shape beneficial gut flora.
Absorption Optimization: AstraGin boosts bioavailability and nutrient uptake across the board.
