Katuki (Picrorhiza kurroa) Extract (Rhizome) - 750mg
A traditional Ayurvedic herb used primarily for liver protection and detoxification.
- Supports liver enzyme balance and healthy bile secretion
- Promotes hepatocyte regeneration and detoxification pathways
- Provides antioxidant defense against free radical damage
- May support healthy inflammatory responses in liver tissues
- Contributes to metabolic waste elimination
Synergy: Combines effectively with Milk Thistle and TUDCA to protect and restore liver cells.
- Dwivedi Y. Indian J Pharmacol. 2007;39(3):125–131.
- Anand V et al. Indian J Biochem Biophys. 1994;31(4):252–255.
- Chander R et al. Phytother Res. 1993;7(4):275–279.
N-Acetyl L-Cysteine (NAC) - 600mg
A cysteine derivative that replenishes intracellular glutathione and supports detoxification.
- Acts as a precursor for glutathione synthesis, the body’s master antioxidant
- Supports phase II liver detoxification pathways
- Helps protect against oxidative damage to liver and kidney cells
- May aid in reducing toxin load and heavy metal burden
- Supports respiratory health and mucolytic activity
Synergy: Works synergistically with Setria Glutathione and Milk Thistle to enhance glutathione status and detoxification.
- Rushworth GF et al. Clin Pharmacol. 2014;6:117–125.
- Samuni Y et al. Biochim Biophys Acta. 2013;1830(5):4117–4129.
- Kelly GS. Altern Med Rev. 1998;3(2):114–127.
Clove (Syzygium aromaticum) Extract (Flower) - 250mg
A botanical extract rich in eugenol, known for antioxidant and antimicrobial effects.
- Provides potent antioxidant capacity to neutralize free radicals
- Supports healthy inflammatory balance
- Contributes to microbial balance in the gut and oral cavity
- May protect liver tissues from oxidative stress
- Supports metabolic and immune function
Synergy: Complements Katuki and NAC by providing broad-spectrum antioxidant defense.
- Chaieb K et al. Phytother Res. 2007;21(6):501–506.
- Gülçin I et al. J Agric Food Chem. 2004;52(21):5039–5045.
- Prashar A et al. Food Chem. 2006;99(4):984–989.
Milk Thistle (Silybum marianum) Extract (Seed) (std. min. 80% Silymarin) - 250mg
A standardized extract supporting liver cell protection and regeneration.
- Stabilizes hepatocyte membranes against toxin damage
- Enhances glutathione content in liver cells
- Supports bile production and digestive detoxification
- Provides anti-inflammatory and antifibrotic activity
- May help regenerate damaged liver tissue
Synergy: Pairs with Katuki and TUDCA for a comprehensive liver-protective matrix.
- Pradhan SC et al. Indian J Med Res. 2006;124(5):491–504.
- Saller R et al. Phytomedicine. 2008;15(5):396–405.
- Polyak SJ et al. Hepatology. 2010;51(6):1919–1926.
Setria (L-Glutathione Reduced) - 250mg
A branded form of bioavailable, reduced glutathione supporting cellular antioxidant defense.
- Replenishes intracellular glutathione stores
- Supports detoxification of heavy metals, xenobiotics, and reactive intermediates
- Protects mitochondrial and DNA integrity
- Contributes to immune resilience and balanced inflammatory responses
- May support skin health and overall oxidative defense
Synergy: Works with NAC and Milk Thistle to maximize glutathione replenishment and detoxification capacity.
- Richie JP et al. Eur J Nutr. 2015;54(2):251–263.
- Allen J et al. Nutrients. 2011;3(4):343–369.
- Witschi A et al. Eur J Clin Pharmacol. 1992;43(6):667–669.
Tauroursodeoxycholic Acid (TUDCA) - 250mg
A bile acid derivative supporting liver cell protection, bile flow, and metabolic health.
- Reduces endoplasmic reticulum stress in hepatocytes
- Promotes bile secretion and reduces cholestasis
- Protects mitochondrial function in liver cells
- May help stabilize cell membranes against toxins
- Supports healthy liver enzyme levels
Synergy: Complements Katuki, Milk Thistle, and NAC for complete liver detoxification and restoration.
- Beuers U et al. Hepatology. 1992;15(3):404–410.
- Amaral JD et al. J Hepatol. 2009;50(4):720–733.
- Rodrigues CM et al. Gastroenterology. 1998;115(3):765–777.
Synergy Overview
Liver Protection & Regeneration: Katuki, Milk Thistle, and TUDCA synergistically protect hepatocytes, enhance bile flow, and restore liver enzyme balance.
Glutathione & Antioxidant Defense: NAC, Setria Glutathione, and Clove provide multi-layered antioxidant support to neutralize free radicals and oxidative stress.
Detoxification & Metabolic Support: NAC and Glutathione promote phase II detoxification, while Milk Thistle and Katuki support metabolic waste elimination.
Mitochondrial & Cellular Stability: TUDCA and Glutathione help preserve mitochondrial integrity and endoplasmic reticulum function under stress.
