Morphogen Nutrition AdaptoGEN

ADAPTOGEN: FUNCTIONAL MUSHROOMS

Healthy Stress Response • Physical + Cognitive Energy • Adrenal Support

ADAPTOGEN is a high-performance formula designed to support your body’s response to stress while promoting endocrine balance, cellular vitality, and long-term resilience. It combines mushroom extracts, adaptogenic herbs, adrenal glandulars, and mitochondrial support compounds to help you stay focused, energized, and grounded. It fuels resilience and recovery while supporting a strong immune system along the way.

Key Benefits:

• Helps regulate cortisol and support adrenal health
  

• Promotes clean energy, focus, and brain performance
  

• Supports immune resilience with functional mushrooms and beta-glucans
  

• Enhances stress tolerance, mood, and cellular recovery

Magnesium (from Aquamin Mg Tg) – 105 mg

A highly bioavailable form of magnesium sourced from red algae, rich in over 72 trace minerals including calcium and boron.

• Supports neurotransmitter balance and promotes relaxation
• Reduces physical and psychological stress through GABA activation
• Enhances sleep quality and muscle recovery
• Crucial for over 300 enzyme systems including energy and nervous system regulation
• Helps regulate cortisol and supports a calm, focused mood

Synergy: Enhances stress resilience when paired with Rhodiola and Reishi. Works with Lion’s Mane to improve calm, clear cognition.

• Firoz M, Graber M. ISRN Pharmacol. 2014;2014:494308
• Tarleton EK et al. Nutrients. 2018;10(9):1176
• de Baaij JHF, et al. Physiol Rev. 2015;95(1):1–46
• Nielsen FH. Nutr Rev. 2010;68(3):120–127
• Volpe SL. Curr Sports Med Rep. 2015

Cordyceps (Cordyceps sinensis) – 1,000 mg

A traditional fungus known for boosting oxygen utilization, ATP production, and adaptogenic energy.

• Enhances ATP and cellular energy for stamina and training output
• Supports adrenal health and endurance under stress
• Promotes VO₂ max and oxygen efficiency
• Aids in immune function and recovery
• Helps restore energy after burnout or overtraining

Synergy: Works with Rhodiola and Maca for complete endurance support. Combines with Reishi and Beta-Glucan to support both performance and immune balance.

• Chen S et al. J Altern Complement Med. 2010;16(3):207–210
• Holliday J, Cleaver M. Mycology. 2004
• Zhu JS et al. J Altern Complement Med. 1998;4(3):289–303

Lion’s Mane (Hericium erinaceus) – 1,000 mg

A nootropic mushroom that stimulates Nerve Growth Factor (NGF) and supports memory and cognitive function.

• Promotes memory, focus, and mental clarity
• Stimulates NGF for neurogenesis and brain repair
• Helps reduce anxiety and enhance mood
• Supports cognitive recovery from stress and sleep loss
• May protect against neurodegenerative decline

Synergy: Enhances cognitive output when combined with Rhodiola and CognatiQ. Works with Magnesium for calming focus and clarity.

• Mori K et al. Biomed Res. 2009;30(4):231–237
• Zhang Z et al. Int J Mol Sci. 2016;17(6):922
• Kawagishi H et al. Biol Pharm Bull. 1991;14(7):659–664
• Ryu S et al. Mycobiology. 2015;43(4):466–473

Reishi (Ganoderma lucidum) (4:1) – 1,000 mg

A calming mushroom known for immune modulation and nervous system support.

• Enhances parasympathetic activity and promotes relaxation
• Reduces anxiety and supports restorative sleep
• Modulates immune system and inflammatory balance
• Supports adrenal function under chronic stress
• Provides triterpenes and polysaccharides for longevity

Synergy: Works with Holy Basil and Magnesium to support calm and recovery. Complements Rhodiola and Beta-Glucan for immune-adaptogen synergy.

• Wachtel-Galor S et al. Herbal Medicine: Biomolecular and Clinical Aspects. CRC Press, 2011
• Boh B et al. Int J Med Mushrooms. 2007;9(3):267–277
• Wasser SP. Int J Med Mushrooms. 2005

Aquamin – 350 mg

A marine-sourced complex of calcium, magnesium, and 72 trace minerals from red algae (Lithothamnion species).

• Supports muscle relaxation and bone mineralization
• Enhances stress resilience via mineral repletion
• Promotes sleep and nervous system stability
• Supports hydration and electrolyte balance
• Aids enzyme function and metabolic efficiency

Synergy: Reinforces the calming and restorative effects of Reishi and Magnesium. Enhances Maca and Siberian Ginseng performance support by reducing fatigue.

• Aslam MN et al. Nutr Res. 2010;30(12):851–856
• Kelly O et al. Nutrients. 2019;11(4):878
• Zittermann A. Nutrients. 2010;2(4):428–445

Rhodiola (Rhodiola crenulata) (std. min. 6% Salidrosides) – 300 mg

A gold-standard adaptogen that regulates cortisol and supports mental and physical stress recovery.

• Reduces fatigue, improves stamina, and restores energy
• Enhances focus, clarity, and productivity under stress
• Normalizes cortisol and enhances emotional balance
• Improves mitochondrial energy output
• Rapid-onset mental performance benefits

Synergy: Synergizes with Cordyceps and Maca for full-spectrum stamina and stress resilience. Works with Lion’s Mane and CognatiQ to optimize cognitive output.

• Panossian A, Wikman G. Phytomedicine. 2010;17(7):481–493
• Spasov AA et al. Phytomedicine. 2000;7(2):85–89
• Darbinyan V et al. Nord J Psychiatry. 2000;54(2):85–91
• Shevtsov VA et al. Phytomedicine. 2003;10(2-3):95–105
• Olsson EM et al. Phytother Res. 2009;23(2):179–185

Adrenal Substance Powder (bovine) – 250 mg

Desiccated glandular tissue derived from bovine adrenal glands, used traditionally to support adrenal recovery and resilience.

• Supports adrenal function and healthy cortisol rhythms
• May improve energy and reduce fatigue from burnout or chronic stress
• Provides naturally occurring adrenal cofactors and enzymes
• Reinforces hormonal balance under prolonged stress exposure
• May enhance tolerance to overreaching in training or lifestyle stress

Synergy: Works synergistically with Rhodiola and Cordyceps to restore HPA axis balance. Complements Holy Basil in supporting emotional stability and cortisol control.

• Wilson JL. Adrenal Fatigue: The 21st Century Stress Syndrome. Smart Publications, 2001
• Gaby AR. Nutritional Medicine. Fritz Perlberg Publishing, 2011

Beta-Glucan (from Saccharomyces cerevisiae) – 250 mg

A naturally occurring polysaccharide that enhances immune function by activating macrophages, NK cells, and dendritic cells.

• Strengthens innate and adaptive immunity
• Enhances response to infection, inflammation, and physical stress
• Supports gut-immune axis integrity
• May reduce severity and duration of respiratory illnesses
• Adaptogenic immune modulation—stimulates when needed, regulates when overactive

Synergy: Works with Reishi for full-spectrum immune balance. Supports gut and adrenal recovery when combined with Magnesium and Rhodiola.

• Vetvicka V, Vetvickova J. Anticancer Res. 2010;30(2):317–321
• Novak M, Vetvicka V. J Am Nutraceutical Assoc. 2008;11(1):42–49
• Murphy EA et al. Med Sci Sports Exerc. 2009;41(8):1465–1471

Holy Basil (Ocimum sanctum) – 250 mg

A sacred Ayurvedic herb shown to lower cortisol, reduce anxiety, and restore physiological balance under stress.

• Reduces cortisol and perceived stress levels
• Improves mood and reduces anxiety
• May enhance resilience to physical and emotional stress
• Supports antioxidant defense and inflammation modulation
• Improves blood sugar and energy stability during adrenal depletion

Synergy: Combines with Reishi and Magnesium to promote deep calm. Enhances the adaptogenic effects of Maca and Adrenal Powder.

• Cohen MM. J Ayurveda Integr Med. 2014;5(4):251–259
• Bhattacharyya D et al. Evid Based Complement Alternat Med. 2014;2014:351957
• Saxena RC et al. J Ethnopharmacol. 1998;61(2):151–156

Maca (Lepidium meyenii) (4:1) – 250 mg

A Peruvian root traditionally used to enhance stamina, hormone balance, and emotional resilience.

• Increases endurance and exercise capacity
• Supports mood and motivation under mental fatigue
• May balance estrogen/testosterone and enhance libido
• Promotes adaptation to stress via HPA axis support
• Helps restore vitality during overtraining or burnout

Synergy: Synergizes with Cordyceps and Rhodiola for complete stress-performance support. Amplifies the mood-balancing effects of Holy Basil and Magnesium.

• Gonzales GF et al. J Ethnopharmacol. 2001;75(2–3):225–229
• Brooks NA et al. Menopause. 2008;15(6):1157–1162
• Stone M et al. J Ethnopharmacol. 2009;122(3):448–452

Siberian Ginseng (Eleutherococcus senticosus) – 200 mg

A non-stimulating adaptogen shown to improve stamina, reduce fatigue, and support mental clarity.

• Enhances resistance to stress-induced fatigue
• Improves working memory, alertness, and cognitive resilience
• Increases physical performance under chronic stress
• Supports immune function and blood glucose regulation
• May aid in recovery from burnout and overwork

Synergy: Complements Rhodiola and Maca for full adaptogenic spectrum. Works with CognatiQ to support clean, non-stimulant focus.

• Panossian A, Wikman G. Phytomedicine. 2009;16(6–7):481–493
• Kennedy DO et al. Psychopharmacology (Berl). 2003;166(3):385–392
• Deyama T et al. Phytother Res. 2001;15(4):337–345

CognatiQ (Coffea arabica whole fruit extract) – 100 mg

A patented extract from the whole coffee fruit (not beans), shown to enhance brain-derived neurotrophic factor (BDNF).

• Increases BDNF to support neuroplasticity and mental sharpness
• Enhances alertness, working memory, and verbal fluency
• Supports long-term brain health and cognitive resilience
• Contains polyphenols and minimal caffeine
• Clean, stimulant-free nootropic profile

Synergy: Potentiated by Lion’s Mane and Rhodiola for full-spectrum cognitive support. Works with CoQ10 and PQQ to support mitochondrial brain energy.

• Small GW et al. Br J Nutr. 2014;111(10):1942–1949
• Reyes-Izquierdo T et al. J Alzheimers Dis. 2013;34(1):147–156

Coenzyme Q10 (Ubiquinone) – 50 mg

A fat-soluble antioxidant and mitochondrial cofactor essential for energy production.

• Enhances cellular energy (ATP) generation
• Protects mitochondria from oxidative stress
• Improves cardiovascular, cognitive, and physical performance
• Supports brain and nervous system energy metabolism
• Promotes resilience during chronic stress and fatigue

Synergy: Works synergistically with PQQ and MitoPrime for mitochondrial rejuvenation. Complements CognatiQ in boosting brain energy and resilience.

• Bhagavan HN, Chopra RK. Mitochondrion. 2007;7(Suppl):S103–S111
• Littarru GP, Tiano L. Biofactors. 2007;32(1–4):119–128

PQQ (Pyrroloquinoline Quinone) – 20 mg

A redox cofactor and antioxidant that stimulates mitochondrial biogenesis and cellular energy renewal.

• Promotes new mitochondrial formation
• Enhances learning, memory, and cognition
• Reduces markers of inflammation and oxidative stress
• Protects neurons and cardiovascular tissues
• Synergistic with CoQ10 for ATP output

Synergy: Part of a mitochondrial trio with CoQ10 and MitoPrime. Supports brain function alongside Lion’s Mane and CognatiQ.

• Chowanadisai W et al. J Nutr Biochem. 2010;21(6):506–513
• Harris CB et al. J Nutr Health Aging. 2013;17(6):443–450

MitoPrime L-Ergothioneine – 5 mg

A potent antioxidant amino acid transported into mitochondria, brain, and immune cells via OCTN1.

• Protects mitochondrial membranes from oxidative stress
• Supports cognitive function and healthy aging
• Enhances immune resilience and redox balance
• Promotes neuroprotection during mental and metabolic stress
• Long half-life and tissue-retention in brain, liver, and bone marrow

Synergy: Enhances mitochondrial synergy with PQQ and CoQ10. Supports stress-adaptive recovery with Rhodiola and Cordyceps.

• Halliwell B et al. FEBS Lett. 2018;592(22):3357–3366
• Cheah IK, Halliwell B. Biochem Biophys Res Commun. 2012;425(3):589–595

Synergy Overview

This adaptogen blend is designed with intelligent ingredient pairing to deliver comprehensive, system-wide benefits across key domains of mental and physical health.

Cognitive and mitochondrial support is provided through the synergistic effects of CognatiQ, Lion’s Mane, Rhodiola, CoQ10, PQQ, and MitoPrime, helping enhance memory, focus, and cellular energy metabolism.

Stress and adrenal recovery is driven by adaptogens such as Rhodiola, Holy Basil, Cordyceps, Maca, Reishi, and adrenal glandulars, which help modulate cortisol and improve resilience under chronic stress.

Energy and endurance are sustained by ingredients like Cordyceps, Maca, Rhodiola, Magnesium, and Siberian Ginseng, supporting mitochondrial ATP production and buffering against physical fatigue.

Mood and calm focus are supported by the synergistic actions of Magnesium, Reishi, Lion’s Mane, and Holy Basil, helping stabilize emotional tone while enhancing clarity and neural balance.

Immune defense is reinforced by immune-modulating compounds including Reishi, Beta-Glucan, and Cordyceps, which promote healthy inflammatory responses during stress exposure.

Finally, mitochondrial resilience is enhanced through the combined activity of CoQ10, PQQ, and MitoPrime, which protect against oxidative stress and promote long-term cellular vitality.

FAQ

Q: What’s the biggest difference in the new version?

A: The updated formula expands far beyond adaptogen support, now including mitochondrial enhancers, immune modulators, and stress-metabolism regulators. It’s now a true full-spectrum neuro-adaptogen with broader use cases and deeper physiological effects.

Q: What new ingredients were added?

A: The new version introduces 6 highly effective ingredients:

• Magnesium (Aquamin MgTG) – brain and muscle relaxation
• Rhodiola extract (6% Salidrosides) – mental energy and stress resilience
• Beta-Glucan (70% 1,3/1,6 from yeast) – immune defense, gut-brain axis
• Maca (4:1 extract) – hormone and mood regulation
• PQQ (Pyrroloquinoline quinone) – brain mitochondrial biogenesis
• MitoPrime L-Ergothioneine – antioxidant, cognition, cellular health

Q: What was removed from the old version?

A:Only Phosphatidylcholine (250 mg) was removed to make room for more potent mitochondrial and adaptogenic compounds. Its role in brain health is now partially replaced by Lion’s Mane, PQQ, and CoQ10.

Q: What stayed the same?

A: Key foundational adaptogens and nootropics were retained:

• Cordyceps (1,000 mg)
• Lion’s Mane (1,000 mg)
• Reishi (1,000 mg)
• Holy Basil (1,000 mg)
• Siberian Ginseng (200 mg, std. 0.8% Eleutherosides)
• CognatiQ Coffee Fruit Extract (100 mg)

These continue to provide reliable cognitive, immune, and stress-balancing effects — now enhanced by synergistic additions.

Q: Is the new version stronger or more effective?

A:Yes. The new version has a broader scope of benefits:

• Neuro-enhancement + stress support + energy metabolism
• Mitochondrial optimization from CoQ10, PQQ, and MitoPrime
• Immune modulation via beta-glucans and adaptogens
• High absorption minerals via Aquamin

Q: How should I use it?

A:

• Consume 1 scoop (6g) morning or midday (not too late due to possible energizing effects)
• With or Without Food: Best with food for magnesium and fat-soluble uptake
• Stacks With: BRAIN, CALM, and any micronutrient supplements like MULTI or OMEGA
• Cycle: Safe for daily use long-term, no cycling needed

Q: Who is this product ideal for?

A:

• Individuals seeking adaptogenic and nootropic support in one
• Anyone under chronic stress, mental fatigue, or immune strain
• Athletes, students, or professionals needing clean cognitive edge
• Those preferring non-stimulant, non-hormonal brain + mood support