Serving Size: 3 capsules | ||
Servings Per Container: 50 | ||
Amount Per Serving | % DV * | |
Joint Glide Mobility Complex (Orioruetart Bkebd | 1005mg | |
Bromelain | 200GDU | †% |
Cetyl Myristoleate 20% | †% | |
Curcuma Longa (as 95% Curcumin) | †% | |
Hyaluronic Acid | †% | |
Bioperine (Piper Nigrum As 95% Piperine) | †% | |
CGC2 Joint Regeneration Matrix (Proprietary Blend) | 795mg | |
Cissus Quadrangularis (as Phytosterols) | †% | |
Ascorbic Acid (as Vitamin C) | 90mg | †% |
Glucosamine Sulfate | †% | |
Chondroitin Sulfate 90% (Bovine) | †% | |
MSM (as Methylsulfonylmethane) | †% | |
* % Daily Value (DV) is based on a 2,000 calorie diet. Your daily values may be higher or lower based on your calorie needs.
† Daily Value (DV) not established. |
||
Other Ingredients: Gelatinn, Titanium Dioxide, Rice Powder |
||
Directions: Take once daily or in two divided doses with fluid, following dosage chart found on bottle. |
||
Warnings: This product is only intended to be consumed by healthy adults 18 years of age or older. Before using this product, seek advice from a physician if you are unaware of you current health condition or have any pre-existing conditions including but not limited to: high or low blood pressure, cardiac arrhythmia, stroke, heat, difficulty urinating due to prostate enlargement or if you are taking an MAO-B inhibitor or nay other prescription or over-the-counter medication. Do not use if you are pregnant, nursing, prone to dehydration or exposed to excessive heat. Do not use if you are allergic to shellfish or products derived from shellfish. Discontinue use and consult your health care professional if sleeplessness, tremors, dizziness, nervousness, headaches or heart palpitations occur or if you experience any adverse reaction to this product. Do not exceed recommended serving size. Before beginning any weight loss program, consult your health care provider. |
Fast-Acting
Joint support Formula
that starts working
Fast!*
- HELPS SUPPORT
JOINT HEALTH* - SUPPORTS A HEALTHY
INFLAMMATION RESPONSE* - SUPPORTS RECOVERY
AFTER HARD TRAINING*
What is Osteo Sport and
What Does it Do?
Osteo-Sport is a state-of-the-art, time-released joint replenishment formula that provides results that improve over extended use.* Osteo-Sport combines a series of carefully selected and proportioned co-factors that provide superior support for joint health.* In fact, Osteo-Sport is the ultimate product for joints because it promotes joint health from multiple angles. The unique blend of ingredients is unlike anything else on the supplement market today.* (1-2)
What Makes OSTEO-SPORT the Most Effective Joint Support on the Market?
A combination of carefully selected ingredients, which are then, incorporated into both our Joint-Glide Mobility Complex and CQC2 Joint Regeneration Matrix blends.
Joint-Glide Mobility Complex
The proprietary Joint-Glide Mobility Complex healthy joints, allowing them to function for your active life.* The complex combines Cetylmyristoleate (CMO), Bromelain, Bioperine, and Hyaluronic Acid to form a matrix that supports greater joint health in all types of activities.*
BROMELAIN
Bromelain is an enzyme derived from pineapples. Bromelain has been successfully used to help support a healthy inflammation response resulting from heavy workouts.* (30-33)
HYALURONIC ACID
Hyaluronic Acid is naturally occurring substance found in many tissues of the body, such as skin and cartilage. Hyaluronic Acid is used to support the health of joints, and is believed to support synovial fluid.* It has also been suggested that Hyaluronic Acid has positive biochemical effects on cartilage cells.* (23-29)
BIOPERINE
Bioperine is a pure form of piperine that is derived from the black pepper that promotes nutrient absorption by interacting with the surface of the intestinal tract, and inhibiting P-Glycoprotein expression. The use of Bioperine greatly enhances the effectiveness of the other compounds in Osteo-Sport by slowing their absorption for more consistent, complete utilization.* (12-14)
CQC2 Joint Regeneration Matrix
The CQC2 Joint Regeneration Matrix of Osteo-Sport contains the blend of cutting-edge herbal components along with several different & science backed substances that promote joint health and longevity.* The matrix utilizes Cissus Quadrangularis, Glucosamine Sulfate, Chondroiton Sulfate, MSM and Ascorbic Acid (Vitamin C) to promote collagen synthesis and support the health of connective tissue.*
CISSUS
Cissus is suggested to support recovery, while at the same time promoting a healthy inflammation response following hard exercise.*
GLUCOSAMINE SULFATE
Glucosamine Sulfate (GS) is another important component of Osteo-Sport and is commonly used for promoting joint health.* GS is mainly used as a precursor for glycosaminoglycans; glycosaminoglycans are important because they are a major active component of joint cartilage. By increasing glycosaminoglycans, supplemental glucosamine may help to support cartilage and other types of connective tissue.* (3-6)
CHONDROITON SULFATE
Chondroitin Sulfate is another beneficial substance found in Osteo-Sport. Chondroitin has a number of positive characteristics, such as supporting healthy inflammation following hard exercise, stimulating the synthesis of proteoglycans and Hyaluronic Acid to promote greater joint health, and decreasing the catabolic activity of chondrocytes.* These aformentioned attributes are important, as they may really help support joint health over time.* (6-11)
MSM (Methysulfonylmethane)
MSM (Methylsulfonylmethane) is also a contributing factor to the effectiveness of Osteo-Sport. Individuals taking MSM have reported increased mobility, and improved physical functioning by delivering a bioavailable source of sulfur components to the body.* The sulfur found in MSM helps maintain the structure of connective tissue by forming cross-linkages through disulfide bonds, which helps strengthen the tissues that make up the joint when used with healthy diet and exercise.* (34-35)
ASCORBIC ACID (Vitamin C)
Ascorbic Acid (Vitamin C) is the final component of Osteo-Sport. Vitamin C is an important compound in immune function and tissue recovery; it is required for the synthesis of important neurotransmitters, amino acids, and the synthesis of connective tissues.* Vitamin C also has strong antioxidant properties, enhances iron absorption, and is needed for the formation of cholesterol-based hormones.* (21-22)
What are some Stacks and Tips to Maximize the Results of OSTEO-SPORT?
For overall complete health, stack Osteo-Sport with our Wellness line products: Bio-Mend, Complete Balance and Omega Essentials
- Jordan KM, Arden NK. EULAR Recommendations 2003: an evidence based approach to the: Report of a Task Force of the Standing Committee for International Clinical Studies Including Therapeutic Trials (ESCISIT). Ann Rheum Dis, 2003; 62:1145–1155
- Zhang W, Moskowitz RW. OARSI, Part I: Critical appraisal of existing treatment guidelines and systematic review of current research evidence activity. Osteoarthritis and Cartilage, 2007; 15: 981- 999
- Persiani S, Roda E, Rovati LC, Locatelli M, Giacovelli G, Roda A. Glucosamine oral bioavailability and plasma pharmacokinetics after increasing doses of crystalline glucosamine sulfate in man. Osteoarthritis Cartilage 2005;13:1041-9.
- Persiani S, Rotini R, Trisolino G, Rovati LC, Locatelli M, Paganini D, Antonioli D, Roda A. Synovial and plasma glucosamine concentrations in patients following oral crystalline glucosamine sulphate at therapeutic dose1 OsteoArthritis and Cartilage (2007) 15, 764-772
- Largo R, et al. Glucosamine inhibits IL-1beta-induced NFkappaB activation in humans. Osteoarthritis Cartilage. 2003 Apr;11(4):290-8.
- Chan PS, et al. Short-term gene expression changes in cartilage explants stimulated with interleukin beta plus glucosamine and chondroitin sulfate. J Rheumatol. 2006 Jul;33(7):1329-40.
- Bassleer C, et al. Stimulation of proteoglycan production by glucosamine sulfate in chondrocytes. Osteoarthritis Cartilage. 1998 Nov;6(6):427-34.
- Dodge GR, et al. Glucosamine sulfate modulates the levels of aggrecan and matrix metalloproteinase-3 synthesized by cultured human. Osteoarthritis Cart. 2003 Jun;11(6):424-32.
- Bourgeois P, Chales G, Dehais J, et al. Efficacy and tolerability of chondroitin sulfate 1200 mg/day vs chondroitin sulfate 3 x 400 mg/day vs placebo. Osteoarthritis Cartilage 1998;6 Suppl A:25-30.
- Braun WA, Flynn MG, Armstrong WJ, et al. The effects of chondroitin sulfate supplementation on indices of muscle damage induced by eccentric arm exercise. J Sports Med Phys Fitness 2005;45(4):553-560.
- Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination. N Engl J Med 2-23-2006;354(8):795-808.
- Influence Of Piperine On The Pharmacokinetics Of Curcumin In Animals And Human Volunteers
- Piperine, An Alkaloid Derived From Black Pepper, Increases Serum Response Of Beta-Carotene During 14-Days Of Oral Beta-Carotene Supplementation
- Vladimir Badmaev, M.D., Ph.D., Muhammed Majeed, Ph.D. and Edward P. Norkus Ph.D.
- Singh SP, Mishra N (1984) An experimental study of analgesic activity of Cissus quadrangularis. Ind. J Pharmac. 162.
- Udupa KN, Guru P (1964) Further studies on the effect of Cissus quadrangularis. Ind. Jour. Med. Res.52(1).
- Udupa KN, Guru P (1964) Biomechanical and calcium studies on the effect of Cissus quadrangularis in fracture repair. . Ind. Jour. Med. Res. 52(5).
- Udupa KN, Guru P (1963) Effect of Cissus quadrangularis Ind. Jour. Med. Res. 51(4).
- Udupa KN (1962) Cissus quadrangularis A clinical study J. Indian Medical Association. 38(11).
- Chopra SS, Patel MR, Gupta LP, Datta IC (1975) Studies on Cissus q in Experimental Fracture Repair: Effect on Chemical parameters in the blood. Ind. Jour. Med. Res. 63(6).
- Vitamin C Against (1996) Irwin Stone.
- Vit. C Requirments: Optimal Health Benefits v. Overdose (http://acu-cell.com/vitc.html) A moderately high does advocacy supporting site.
- Kakizaki, I., Kojima, K., Takagaki, K., Endo, M., Kannagi, R., Ito, M., Maruo, Y., Sato, H., Yasuda, T., Mita, S., Kimata, K. and Itano, N. (2004) A novel mechanism for the inhibition of hyaluronan biosynthesis by 4-methylumbelliferone. J. Biol. Chem. 279, 33281–33289.
- Yoshihara S, Kon A, Kudo D, Nakazawa H, Kakizaki I, Sasaki M, Endo M, Takagaki K., A hyaluronan synthase suppressor, 4-methylumbelliferone, inhibits liver metastasis of melanoma cells. FEBS Lett 2005;579:2722–6. PMID: 15862315
- De Andrés Santos MI, Velasco-Martín A, Hernández-Velasco E, Martín-Gil J, Martín-Gil FJ (1994). "Thermal behaviour of aqueous solutions of sodium hyaluronate from different commercial sources".Thermochim Acta 242: 153-160. doi:10.1016/0040-6031(94)85017-8.
- Shu XZ, Ghosh K, Liu Y, Palumbo FS, Luo Y, Clark RAF, Prestwich GD: Attachment and spreading of fibroblast on an RGD peptide-modified injectable hyaluronan hydrogel. J Biomed Materials Res, 68:365-75, 2004.
- Stern R (August 2004). "Hyaluronan catabolism: a new metabolic pathway". Eur J Cell Biol 83 (7): 317-25. doi:10.1078/0171-9335-00392. PMID 15503855.
- Holmes et al. (1988) Hyaluronic acid in human articular cartilage. Age-related changes in content and size. Biochem J 250:435-441.
- Averbeck M et al. (2007) Differential regulation of hyaluronan metabolism in the epidermal and dermal compartments of human skin by UVB irradiation. J Invest Dermatol 127:687-697.
- Heinicke, R.M. and W.A. Gortner. 1957. Stem bromelain-a new protease preparation from pineapple plants. Econ. Bot. 11 (3): 225-234.
- Gutfreund A, Taussig S, Morris A (1978). "Effect of oral bromelain on blood pressure and heart rate of hypertensive patients". Hawaii medical journal 37 (5): 143-6. PMID 659096.
- Gregory S. Kelly, N.D. Bromelain: A Literature Review and Discussion of its Therapeutic Applications (Alt Med Rev 1996;1(4):243-257
- Brien S, Lewith G, Walker A (2004). "Bromelain: a Review of Clinical Studies". Evidence-based complementary and alternative medicine: eCAM. 1 (3): 251-257.PMID 15841258.
- Barrager E, Veltmann JR, Schauss AG, Schiller RN. A multi-centered, open label trial on the safety and efficacy of methylsulfonylmethane in the treatment of seasonal allergic rhinitis. J Altern Complement Med2002;8:167–74. PMID 12006124
- Kim LS, Axelrod LJ, Howard P, Buratovich N, Waters RF. Efficacy of methylsulfonylmethane (MSM) knee: a pilot clinical trial. Cartilage 2006;14(3):286–94. PMID 16309928