Beta-carotene is a toxic, fat soluble substance that should not be supplemented. It turns into two retinaldehyde molecules in the body, which converts to the fat soluble alcohol retinol (vitamin A), which many individuals already have too much of.
Beta-carotene increases mortality, cancer, and risk of bone fractures
There are several meta-analyses covering dozens of studies showing increased all-cause mortality, cancer (especially lung cancer), and risk of bone fractures from beta-carotene supplementation:
- https://pubmed.ncbi.nlm.nih.gov/12814711/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8407395/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3765487/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5227980/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5615580/
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9343755/
This is doubly true if you are a smoker - do not take beta-carotene if you smoke!
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